Benzotiyazol İçeren Yeni Schiff Bazlarının Sentezi ve Bazı Metal İyonları Varlığında Florimetrik Davranışlarının Araştırılması
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Dosyalar
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi Fen Bilimleri Enstitüsü
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Schiff bazları, aldehit veya ketonların primer aminlerle genellikle alkollü çözeltide ve nötral
ortamda reaksiyona girmesi ile oluşan, kondensasyon reaksiyonu sonucu yapısında azometin veya imin
grubu olarak adlandırılan karbon-azot (C=N) çift bağı bulunduran bileşiklerdir. Schiff bazı bileşikleri
kararlı, kolay sentezlenebilen bileşiklerdir. Bunun yanı sıra, kimyanın pek çok alanında, endüstride, tıp ve
eczacılıkta geniş kulanım alanlarına sahip olmaları bu bileşiklere olan ilgiyi artırmış, onları farklı
alanlarda yaygın olarak kullanılabilir hale getirmiştir. Schiff bazları epoksidasyon reaksiyonlarında
katalizör, iletken polimerlerin sentezinde monomer olarak; antifungal, antibakteriyel, antimikrobiyal ve
bazı oksidatif radikal türlerine karşı antioksidan olarak kullanılmaktadır. Son yıllarda Schiff Bazı temelli
moleküler sensörler bilim insanlarının en çok üzerinde durduğu konulardan birisi olmuştur.
Bu tez çalışmasında p-hidroksi benzaldehitten literatür bilgileri ışığında hidrazon türevli bileşik
elde edildi. Bu bileşikten benzotiyazol türevli yeni Schiff bazı reseptörlerin (N2 ve N3) hazırlanması ve
bu reseptörlerin farklı metal iyonlarına karşı florimetrik davranışlarının araştırılması gerçekleştirilmiştir.
Yeni sentezlenen Schiff bazı reseptörlerinin (N2 ve N3) yapıları spektroskopik teknikler (1
H-NMR, 13CNMR ve FT-IR ) yardımıyla karakterize edilmiştir. Hazırlanan reseptörlerin farklı çözücü ortamlarında
metal iyonlarına karşı florimetrik olarak seçimli olup olmadığı incelenmiştir. Yeni hazırlanan N2 Schiff
bazının saf EtOH çözücü ortamında Al3+ ve Zn2+ metal iyonlarına karşı florimetrik olarak seçimli olduğu
tespit edilmiştir. Sentezlenen N3 Schiff bazının ise EtOH/H2O (70/30) çözücü ortamında sadece Al3+
iyonuna karşı florimetrik olarak seçimli olduğu gözlenmiştir. Sentezlenen N2 ve N3 bileşiklerinin Al3+ ve
Zn2+ metal iyonlarına karşı seçimlilik davranışları floresans deneyleri ile araştırılmıştır.
Schiff bases are compounds that are formed by the reaction of aldehydes or ketones with primary amines, usually in alcoholic solution and in a neutral environment, and contain carbon-nitrogen (C=N) double bonds, called the azomethine or imine group, in their structure because of the condensation reaction. Schiff base compounds are stable, easily synthesized compounds. In addition, the fact that they have wide usage areas in many fields of chemistry, industry, medicine, and pharmacy has increased the interest in these compounds and made them widely used in different fields. Schiff bases as catalysts in epoxidation reactions, as monomers in the synthesis of conductive polymers; It is used as antifungal, antibacterial, antimicrobial and antioxidant against some types of oxidative radicals. In recent years, Schiff Base-based molecular sensors have been one of the most emphasized topics by scientists. In this thesis study, a hydrazone-derived host with literature information was obtained from phydroxy benzaldehyde. The preparation of new benzothiazole derived Schiff base receptors (N2 and N3) from this compound and the investigation of the fluorimetric behavior of these receptors against different metal ions were carried out. The structures of newly synthesized Schiff molar receptors (N2 and N3) were characterized with the help of spectroscopic techniques (1 H-NMR, 13C-NMR and FT-IR). It was investigated whether the prepared receptors were fluorimetrically selective against metal ions in different solvent environments. It has been determined that the newly prepared N2 Schiff base is fluorimetrically selective against Al3+ and Zn2+ metal ions in only EtOH solvent medium. It was observed that the synthesized N3 Schiff base was fluorimetrically selective against only Al3+ ion in EtOH/H2O (70/30) solvent medium. The selectivity behavior of the synthesized N2 and N3 compounds against Al3+ and Zn2+ metal ions was investigated by fluorescence experiments.
Schiff bases are compounds that are formed by the reaction of aldehydes or ketones with primary amines, usually in alcoholic solution and in a neutral environment, and contain carbon-nitrogen (C=N) double bonds, called the azomethine or imine group, in their structure because of the condensation reaction. Schiff base compounds are stable, easily synthesized compounds. In addition, the fact that they have wide usage areas in many fields of chemistry, industry, medicine, and pharmacy has increased the interest in these compounds and made them widely used in different fields. Schiff bases as catalysts in epoxidation reactions, as monomers in the synthesis of conductive polymers; It is used as antifungal, antibacterial, antimicrobial and antioxidant against some types of oxidative radicals. In recent years, Schiff Base-based molecular sensors have been one of the most emphasized topics by scientists. In this thesis study, a hydrazone-derived host with literature information was obtained from phydroxy benzaldehyde. The preparation of new benzothiazole derived Schiff base receptors (N2 and N3) from this compound and the investigation of the fluorimetric behavior of these receptors against different metal ions were carried out. The structures of newly synthesized Schiff molar receptors (N2 and N3) were characterized with the help of spectroscopic techniques (1 H-NMR, 13C-NMR and FT-IR). It was investigated whether the prepared receptors were fluorimetrically selective against metal ions in different solvent environments. It has been determined that the newly prepared N2 Schiff base is fluorimetrically selective against Al3+ and Zn2+ metal ions in only EtOH solvent medium. It was observed that the synthesized N3 Schiff base was fluorimetrically selective against only Al3+ ion in EtOH/H2O (70/30) solvent medium. The selectivity behavior of the synthesized N2 and N3 compounds against Al3+ and Zn2+ metal ions was investigated by fluorescence experiments.
Açıklama
Anahtar Kelimeler
Benzotiyazol, Floresans, Metal, Organik Sentez, Schiff Bazı, Spektroskopik Teknikler, Benzothiazole, Fluorescence, Metal Ion,, Organic Synthesis, Schiff Bases, Spectroscopic Techniques
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Taşpınar, N., (2023). Benzotiyazol İçeren Yeni Schiff Bazlarının Sentezi ve Bazı Metal İyonları Varlığında Florimetrik Davranışlarının Araştırılması. (Yüksek Lisans Tezi). Selçuk Üniversitesi, Fen Bilimleri Enstitüsü, Konya.
