A comparative investigation of anti-Mullerian hormone (AMH) and various biochemical parameters in patients with cryptorchidism, oligospermia, or varicocele

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Tarih

2012

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Aim: To investigate the serum AMH and various biochemical parameter levels in patients with cryptorchidism, oligospermia, or varicocele. Materials and methods: This study included 100 participants, divided into 5 groups: cryptorchidism (n = 20), varicocele (n = 20), oligospermia (n = 20), and 2 control groups [control 1,8-12 years old (n = 20) and control 2, 18-24 years old (n = 20)]. Using the blood samples drawn from both patient and control groups, AMH, testosterone, FSH, LH, and prolactin parameters were investigated. Results: AMH values measured were found to be 73.04 +/- 44.5 ng/mL and 84.81 +/- 59.1 ng/mL in 20 children with cryptorchidism and 20 healthy children (both groups aged between 8 and 12 years), respectively (P = 0.56). In the present study, AMH values were found to be 5.19 +/- 4.9 ng/mL and 7.66 +/- 5.6 ng/mL in 20 patients with oligospermia and 20 healthy individuals (both groups aged between 18 and 24 years), respectively (P = 0.10). AMH values in 20 patients with varicocele and 20 healthy controls aged between 18 and 24 years were determined to be 7.15 +/- 5.8 ng/mL and 7.66 +/- 5.6 ng/mL, respectively (P = 0.82). No significant P values were determined, but the decrease in values was remarkable. Conclusion: New studies with larger number of participants are needed in order to determinate AMH levels in patients with varicocele, cryptorchidism, or varicocele for diagnostic criteria.

Açıklama

Anahtar Kelimeler

Anti-Mullerian hormone, varicocele, infertility, cryptorchidism

Kaynak

TURKISH JOURNAL OF MEDICAL SCIENCES

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

42

Sayı

3

Künye