A COMPARISON OF TWO DIFFERENT SEDATION TECHNIQUES IN GERIATRIC PATIENTS FOR ENDOSCOPIC UROLOGICAL SURGERY
Küçük Resim Yok
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
GUNES KITABEVI LTD STI
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction: In this study, we evaluated the effectiveness and safety of intravenous propofol-fentanyl and ketamine-midazolam combinations for procedural sedation and analgesia in elderly patients undergoing urological endoscopic surgery. Materials and Method: This prospective study enrolled 80 patients aged 60-80 years ASA I-III requiring endoscopic urological procedures. Patients received intravenous bolus doses of either fentanyl 1 mu g.kg-1 and propofol 1-2 mg.kg-1 in group P or ketamine 1-1.5 mg.kg-1 and midazolam 0.1 mg.kg-1 in group K titrated according to Ramsay sedation scale in the range of 3-4. Results: There were no differences in vital signs, operating times and demographic variables. Time to Aldrete score >= 8 was similar in two groups. Time to PADSS >= 9 was significantly longer in group K than group P (p<0.05). The frequency of vertigo, nausea, vomiting, visual disturbances, laryngeal spasm and hallucinations were higher in group K (p<0.05). But pain of injection and respiratory depression were more frequent in group P (p<0.05). Excessive salivation, tachycardia, bradycardia, hypotension, hypertension were similar in both groups. Conclusion: Hemodynamic changes and degrees of sedation showed that propofol-fentanyl and ketamine-midazolam combinations can safely be used in geriatric patients undergoing endoscopic urological procedures. However, in the propofol-fentanyl group the incidence of side effects were lower and the recovery period was shorter than the ketamine-midazolam group.
Açıklama
Anahtar Kelimeler
Propofol, Ketamine, Conscious Sedation, Geriatrics
Kaynak
TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
15
Sayı
1
