The relationship of metabolic syndrome, serum leptin levels and treatment in bipolar disorder

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dc.contributor.authorYumru, Mehmet
dc.contributor.authorSavas, Esen
dc.contributor.authorGergerlioglu, H. Serdar
dc.contributor.authorBasarali, Kemal
dc.contributor.authorKalenderoglu, Aysun
dc.contributor.authorSavas, Haluk A.
dc.contributor.authorBueyuekbas, Sadik
dc.date.accessioned2020-03-26T17:28:14Z
dc.date.available2020-03-26T17:28:14Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: In this study we aimed to evaluate the relationship between serum leptin. levels, metabolic syndrome and treatment in bipolar patients. Method: Sixty bipolar I disorder (BD) patients were enrolled; 29 patients were on mood stabilizer (MS) (lithium, valproic acid, carbamazepin, and lamotrigine) treatment, 31 patients were on atypical antipsychotics (AA) (risperidone, quetiapine, and olanzapine) for at least 3 months. Metabolic syndrome (MetS) was evaluated according to NCEP ATP III (Adult Treatment Protocol of the National Cholesterol Education Programme) criteria. Results: 36.7% of the patients were recognized as MetS. The AA subgroup had significantly more MetS than MS. Abdominal obesity was significantly correlated with leptin levels in BD. No significant association was found between MetS and leptin levels in BD. Discussion: AA taking bipolar patients had higher MetS rates. However, there was no significant difference among AAs for inducing MetS. Leptin levels were significantly correlated with abdominal obesity in bipolar patients but seem not to be associated with MetS.en_US
dc.identifier.endpage83en_US
dc.identifier.issn1017-7833en_US
dc.identifier.issue2en_US
dc.identifier.startpage79en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22742
dc.identifier.volume18en_US
dc.identifier.wosWOS:000258118600002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherKURE ILETISIM GRUBU A Sen_US
dc.relation.ispartofKLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectbipolar disorderen_US
dc.subjectmetabolic syndromeen_US
dc.subjectleptinen_US
dc.subjectatypical antipsychoticsen_US
dc.titleThe relationship of metabolic syndrome, serum leptin levels and treatment in bipolar disorderen_US
dc.typeArticleen_US

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