Ratautaite, VilmaTopkaya, Seda NurMikoliunaite, LinaOzsoz, MehmetOztekin, YaseminRamanaviciene, AlmiraRamanavicius, Arunas2020-03-262020-03-2620131040-03971521-4109https://dx.doi.org/10.1002/elan.201300063https://hdl.handle.net/20.500.12395/29655In this study graphite electrodes modified by a thin DNA-imprinted polypyrrole layer, which was able to bind specific target-DNA, are reported. For this aim, electrochemical synthesis of polypyrrole was performed on a pencil graphite electrode by cyclic voltammetry (CV) or by potential pulse sequences (PPS). The modified electrode surface was used for electrochemical determination of target-DNA by differential pulse voltammetry. According to our best knowledge this is a first report on the application of DNA-imprinted polymer for the determination of target-DNA. The results showed that the molecularly imprinted polypyrrole (MIPPy) layer that formed on the carbon electrode surface was sensitive for target-DNA, while the nonimprinted polypyrrole layer was not sensitive to the same target-DNA. Comparison of electrodes modified using PPS and CV techniques is presented.en10.1002/elan.201300063info:eu-repo/semantics/closedAccessMolecularly imprinted polymers (MIPs)PolypyrroleDNAElectrochemical DNA biosensorDNA-imprinted polymerArticle25511691177Q2WOS:000318798000011Q2