Leonardı, AndreaSilva, DianaPerez Formigo, DanielBozkurt, BanuSharma, VibhaAllegri, PiaRondon, CarmenCalder, VirginiaRyan, DermotL. Kowalsk, MarekDelgado, LuisDoan, SergeL. Fauquert, Jean2020-03-262020-03-262019Leonardı, A., Silva, D., Perez Formigo, D., Bozkurt, B., Sharma, V., Allegri, P., Rondon, C., Calder, V., Ryan, D., L. Kowalsk, M., Delgado, L., Doan, S., L. Fauquert, J. (2019). Management of Ocular Allergy. Allergy: European Journal of Allergy and Clinical Immunology, 74,(9), 1611-1630.0105-4538https://dx.doi.org/10.1111/all.13786https://hdl.handle.net/20.500.12395/38458The treatment and management of ocular allergy (OA) remain a major concern for different specialties, including allergists, ophthalmologists, primary care physicians, rhinologists, pediatricians, dermatologists, clinical immunologists, and pharmacists. We performed a systematic review of all relevant publications in MEDLINE, Scopus, and Web Science including systematic reviews and meta-analysis. Publications were considered relevant if they addressed treatments, or management strategies of OA. A further wider systematic literature search was performed if no evidence or good quality evidence was found. There are effective drugs for the treatment of OA; however, there is a lack an optimal treatment for the perennial and severe forms. Topical antihistamines, mast cell stabilizers, or double-action drugs are the first choice of treatment. All of them are effective in reducing signs and symptoms of OA. The safety and optimal dosing regimen of the most effective topical anti-inflammatory drugs, corticosteroids, are still a major concern. Topical calcineurin inhibitors may be used in steroid-dependent/resistant cases of severe allergic keratoconjunctivitis. Allergen-specific immunotherapy may be considered in cases of failure of first-line treatments or to modify the natural course of OA disease. Based on the current wealth of publications and on the collective experience, recommendations on management of OA have been proposed. © 2019 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.en10.1111/all.13786info:eu-repo/semantics/openAccessallergic conjunctivitismanagementocular allergysystematic reviewtreatmentArticle7491611163030887530Q1WOS:000582627000001Q1