Baltaci, AKMogulkoc, RHalifeoglu, I2020-03-262020-03-2620050163-4984https://dx.doi.org/10.1385/BTER:104:1:041https://hdl.handle.net/20.500.12395/19715The effects of zinc deficiency and supplementation on plasma leptin levels were studied in Sprague-Dawley rats. After 6 wk on a zinc-deficient diet containing 0.65 ppm Zn/g, the mean body weight was significantly lower than that of normal or zinc-supplemented rats, which showed no difference among them. The plasma leptin and zinc levels were lowest in zinc-deficient animals and highest in those that received a normal diet and daily intraperitioneal injections of 3 mg Zn/kg. These results indicate that zinc deficiency leads to a significant inhibition in plasma leptin levels, whereas zinc supplementation significantly increases plasma leptin.en10.1385/BTER:104:1:041info:eu-repo/semantics/openAccesszinc deficiency and supplementationleptin, ratArticle1041414615851831WOS:000228961800005Q4