Çolakoğlu, Mehmet C.Arslan, EmineGezginç, KazımÇelik, ÇetinÇapar, MetinAköz, MehmetAcar, Ali2020-03-262020-03-2620040-444-51546-10531-5131https://dx.doi.org/10.1016/j.ics.2004.06.020https://hdl.handle.net/20.500.12395/1920018th World Congress on Fertility and Sterility -- MAY 23-28, 2004 -- Montreal, CANADAObjective: The aim of this study was to investigate lupus anticoagulant (LA), anticardiolipin antibody (ACA), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) serum levels in 40 pregnant and 20 non-pregnant women. Materials and methods: The women were divided into three groups. The first group consisted of 20 pregnant women of less than 20 gestational weeks and with a past history of habitual abortion. The second group consisted of 20 non-pregnant patients with a past history of habitual abortion. The third group consisted of 20 healthy pregnant women. Result: LA was found in only one patient in Group 2. ACA IgG positivity was found in one patient in Group 1, three patients in Group 2 and one patient in Group 3. Mean ACA IgG was highest in Group 2. High serum TNF-a levels were found in 12 (60%), 6 (30%) and 2 (10%) women in Groups 1, 2 and 3, respectively. Conclusion: We propose that cytokines, especially TNF-alpha, were found to be related to pregnancy loss. (C) 2004 Elsevier B.V. All rights reserved.en10.1016/j.ics.2004.06.020info:eu-repo/semantics/openAccessrecurrent miscarriageLAACATNF-alphaIL-6Conference Object12715053N/AWOS:000226551500013N/A