Yılmaz, Fatma HilalYuca, Sevil ArıVatansev, HüsamettinCimbek, Emine AyçaŞen, YasarYılmaz, IsaAkyürek, Fikret2020-03-262020-03-262017Yılmaz, F. H., Yuca, S. A., Vatansev, H., Cimbek, E. A., Şen, Y., Yılmaz, İ., Akyürek, F., Arslan, D., Çimen, D., Yorulmaz, A. (2017). Heart-Type Fatty Acid Binding Protein Level as a Tool in Identification of Early Cardiac Effects of Diabetic Ketoacidosis. Journal of Clinical Research in Pediatric Endocrinology, 9(2), 118-123.1308-57271308-5735https://dx.doi.org/10.4274/jcrpe.3961https://hdl.handle.net/20.500.12395/35165Objective: This study aimed to measure the serum levels of heart-type fatty acid binding protein (H-FABP) in patients presenting with diabetic ketoacidosis (DKA) and diabetic ketosis (DK) and to determine its role in identifying early-period cardiac ischemia. Methods: This prospective study included 35 patients diagnosed with DKA, 20 patients diagnosed with DK, and 20 control subjects. H-FABP, creatine kinase-MB (CK-MB), and troponin I levels were investigated at presentation in patients with DKA and DK and in the control group. H-FABP values were measured again after acidosis correction in the DKA patients. Results: No statistically significant differences were found with respect to troponin I and CK-MB within the groups. The H-FABP values of DKA patients at presentation were found to be significantly higher than those of DK patients and the control group (p = 0.015). The H-FABP value of the DKA group was also found to be significantly higher than the value at hour 36 after acidosis correction (p = 0.0001). Conclusion: We would like to propose H-FABP as a potential marker for indicating myocardial ischemia.en10.4274/jcrpe.3961info:eu-repo/semantics/openAccessHeart-type fatty acid binding proteinchilddiabetic ketoacidosisArticle9211812328077344Q2WOS:000406446700005Q3