Balcı, OsmanÖzdemir, SunaMahmoud, Alaa S.Acar, Ali2020-03-262020-03-262010Balcı, O., Özdemir, S., Mahmoud, A. S., Acar, A., (2010). Induction of Labor With Vaginal Misoprostol Plus Oxytocin Versus Oxytocin Alone. GORM:Gynecology Obstetrics & Reproductive Medicine, (110), 64-67. Doi: 10.1016/j.ijgo.2010.02.0041300-47512602-4918http://www.trdizin.gov.tr/publication/paper/detail/TVRJeU5UZzVPUT09https://hdl.handle.net/20.500.12395/24316Objective: To compare the effect of an oxytocin infusion alone or preceded by an intravaginal application of misoprostol for labor induction in women with term pregnancies and a low Bishop score. Methods: This study randomized 100 multiparous women with singleton pregnancies over 38 weeks and a Bishop score less than 6 to receive either a single 50-µg dose of misoprostol intravaginally 3 hours before initiation of the oxytocin infusion or only an oxytocin infusion. The time from induction to delivery, the route of delivery, and maternal and fetal outcomes were analyzed. Results: The mean time from induction to delivery was 9.36± 1.97 hours in the misoprostol plus oxytocin group and 11.08± 3.23 in the oxytocin alone group (P= 0.002). The rates of vaginal delivery, 1- and 5-minute Agpar scores, placental abruption, and postpartum hemorrhage were similar between the 2 groups, as were the rates of admission to the neonatal intensive care unit. There were no cases of perinatal asphyxia. Conclusion: A 50-µg intravaginal application of misoprostol before starting the oxytocin infusion is a more effective method of labor induction than an oxytocin infusion alone for our study population.eninfo:eu-repo/semantics/openAccessKadın Hastalıkları ve DoğumInduction of laborMisoprostolOxytocinArticle110646720347088WOS:000279568900016N/A