Balci S.S.2020-03-262020-03-2620130025-7826https://hdl.handle.net/20.500.12395/30032Aim: The purpose of this study was to examine sex differences in changes in lipid and protein oxidation and antioxidant in plasma due to acute exhaustive exercise in young people. Methods: Forty-eight young men (21.7 ± 0.5 years old, n = 24) and women (21.2 ± 0.5 years old, n = 24) participated voluntarily in this study. Venous blood was collected immediately before, immediately after, and thirty minutes after acute exhaustive exercise in order to measure the plasma levels of thiobarbituric acid reactive substances (TBARS), protein carbonyl (PC), creatine kinase (CK), total antioxidant capacity (TAC), glutathione (CSH), and superoxide dismutase (SOD). Results: The effect of acute exhaustive exercise on levels of TBARS, PC, CK, TAC, CSH and activity of SOD was significant (P< 0.05). After exhaustive exercise TBARS levels significantly decreased and, PC and CK levels increased. However, the changes in levels of TBARS, PC, CK and TAC during and after exhaustive exercise were similar in men and women (P> 0.05). On the other hand, the changes in SOD activity and GSH level after exhaustive exercise were different in sex groups (P< 0.05). The SOD activity and GSH level significantly increased after exercise in women (P< 0.05) and did not significantly change in men. Conclusion: The results suggest that sex differences should be considered when evaluating the effects of acute exercise on oxidative stress.itinfo:eu-repo/semantics/closedAccessAntioxidantsExerciseOxidative stressSex characteristicsArticle663339350Q3