Demir, O.Yazar, E.Altunok, V.Elmas, M.Özdemir, V.2020-03-262020-03-262001Demir, O., Yazar, E., Altunok, V., Elmas, M., Özdemir, V., (2001). Effect of Phenobarbital on Antioxidant Enzyme Activities and Blood Gas Parameters in Balb/C Mice. Revue De Medecine Veterinaire, 152(10), 723-726.0035-1555https://hdl.handle.net/20.500.12395/17529In this study, effect of Phenobarbital was investigated on antioxidant enzyme activities and blood gas parameters in Balb/C mice. Forty male Balb/C mice were used. Ten mice were served as a control group, and thirty mice were administered phenobarbital (80 mg/kg body weight, orally, single administration). Blood, brain and liver samples were taken at 6, 12 and 24 hours after administration. Brain and liver tissues superoxide dismutase and glutathione peroxidase activities were measured by spectrophotometry, and blood gas parameters were measured with blood gas analyzer. As results, phenobarbital caused temporary respiratory acidosis and a decrease in brain tissue superoxide dismutase activity.eninfo:eu-repo/semantics/closedAccessPhenobarbitalSuperoxide DismutaseGlutathione PeroxidaseBlood Gas ParametersMiceArticle15210723726Q3WOS:000172514700008Q4