Kocabaş, ErdalDurmaz, MustafaAlpaydın, SabriSirit, AbdulkadirYılmaz, Mustafa2020-03-262020-03-2620080899-00421520-636Xhttps://dx.doi.org/10.1002/chir.20483https://hdl.handle.net/20.500.12395/22251Novel chiral mono and diamide derivatives of calix[4]arene have been prepared from the aminolysis reaction of 5,11,17,23-tetra-tert-butyl-25,27-dietboxycarbonyl-methoxy-26,28-dihydroxycalix[4]arene 1 and 25,27-diethoxycarbonyl-methoxy-26,28-dihydroxycalix[4]arene 2 with chiral (S)-(-)-1-phenylethylamine (PEA) and (1S,2S)-(+)-2-amino-1-(4-nitrophenyl)-1,3-propanediol, respectively. Spectrophotometric titrations have been performed in CHCl3 at 20-30 degrees C in order to obtain the binding constants (K) and the thermodynamic quantities (Delta H and Delta S) for the stoichiometric 1:1 inclusion complexation of various chiral amines with these new host compounds. Preliminary experiments were undertaken to confirm the complexation properties of receptors 9 and 13 with PEA by H-1 NMR in CDCl3 at room temperature. The molecular recognition abilities and enantioselectivities for guests (R and S)-(x-PEA and (R and S)-cyclohexylethylamine (CHEA) are discussed from a thermodynamic point of view.en10.1002/chir.20483info:eu-repo/semantics/closedAccesschiral calix[4]arenemonoamidediamidemolecular recognitionUV-vis titrationArticle201263417924427Q3WOS:000252130200005Q2