Kheirandish, RezaSami, MasoudGhanbarpour, RezaAlidadi, Soodeh2022-12-302022-12-302013Kheirandish, R., Sami, M., Ghanbarpour, R., Alidadi,S., (2013). Pulmonary nocardiosis in a fat-tailed sheep. Eurasian Journal Of Veterinary Sciences, 29 (4), 220-224.1309-69582146-1953https://hdl.handle.net/20.500.12395/44124Nocardia spp. sığırlarda mastit, kutanöz ve subkutanöz apseler, pneumoni ve yaygın hastalıklara neden olmaktadır. Bir koyunda Nocardia spp.’ya bağlı pulmoner enfeksiyon belirlendi. Makroskopide hasta akciğerinde çoklu beyaz, sabit, küçük nödüller gözlendi. Mikroskopide makrofajlı poligranulomatöz yangı odakları, çok çekirdekli (langhans-type) dev hücreler ve rozet şeklinde eosinofilik (Splendor-Hoeppli reaction) bölgeler gözlendi. Akciğer doku örnekleri sığır kanlı agarda 37 o C’de 48-72 saat aerobik şartlarda inkübe edildi. Dokular Gram ve modifiye Zeihl-Neelsen ile boyandı. Bakteriyolojik incelemede ince çok sayıda, gram-pozitif, boncuklu, filamentli ve non-asit hızlı organizmalar olduğunu gözlendi. Sonuçta bakteriyolojik, histopatalojik ve makroskobik bulgular pulmonary nokardiozis olgusunu doğruladı ve bu vaka İran’da koyunda gözlenen ilk pulmonar nokardiozis olgusudurNocardia spp. are known as causes of bovine mastitis, pneumonia, cutaneous or subcutaneous abscesses and disseminated disease. Pulmonary infection by Nocardia spp. was diagnosed in a sheep. Grossly, the animal had multiple white, firm, and small nodules in the lung. Microscopically, the nodules consisted of foci of pyogranulomatous inflammation with the presence of macrophages, multinucleated (langhans-type) giant cells and eosinophilic amorphous material with rosette-shape configurations (Splendore-Hoeppli reaction). Tissue samples of the lung were streaked onto bovine blood agar, incubated at 37 o C for 48-72 hours under aerobic condition, and stained with Gram and modified Zeihl-Neelsen staining. Bacteriological investigations confirmed numerous thin, gram-positive, beaded, branching, filamentous and nonacid fast organisms. Finally, on the basis of characteristic gross, histopathological and bacteriological findings pulmonary nocardiosis was diagnosed, and this is the first reported case of pulmonary nocardiosis in a sheep in Iran.eninfo:eu-repo/semantics/openAccessPulmonar nokardioziskoyunPulmonary nocardiosissheepArticle294220224