Karabağlı, HakanGenç, AliKarabağlı, PınarAbacıoğlu, UfukŞeker, AşkınKılıç, Türker2020-03-262020-03-262010Karabağlı, H., Genç, A., Karabağlı, P., Abacıoğlu, U., Şeker, A., Kılıç, T., (2010). Outcomes of Gamma Knife Treatment for Solid Intracranial Hemangioblastomas. Journal of Clinical Neuroscience, (17), 706-710. Doi: 10.1016/j.jocn.2009.09.0280967-58681532-2653https://dx.doi.org/10.1016/j.jocn.2009.09.028https://hdl.handle.net/20.500.12395/25139The aim of this study was to examine the results of gamma knife radiosurgery for 13 patients with residual/recurrent or newly diagnosed solid hemangioblastomas. The 13 patients had 34 solid hemangioblastomas, and all patients underwent gamma knife radiosurgery. Seven patients had von Hippel-Lindau disease and six had sporadic disease. When individual lesions were considered, the overall mean dose at the tumor periphery was 15.8 Gy (range: 12-25 Gy) and the average maximum tumor dose was 31.6 Gy (range: 24-50 Gy). The mean duration of follow-up with MRI was 50.2 months. At the last follow-up evaluation, growth control was achieved for all tumors (partial remission in three tumors [8.8%] and no change in 31 tumors [91.2%]). No radiation-related complications were encountered. Our findings reinforce the view that gamma knife radiosurgery is effective and safe for the management of solid hemangioblastomas with a diameter less than 3 cm, whether they are sporadic or associated with von Hippel-Lindau disease. The high response rate and lack of any radiation-induced side-effects confirms the suitability of the doses used in the present study.en10.1016/j.jocn.2009.09.028info:eu-repo/semantics/openAccessGamma knifeHemangioblastomaRadiosurgeryVon Hippel-Lindau diseaseArticle1770671020303274Q2WOS:000278084900005Q4