Acar, HasanAcar, Aynur2020-03-262020-03-2619970141-9854https://dx.doi.org/10.1046/j.1365-2257.1997.00186.xhttps://hdl.handle.net/20.500.12395/16567We have used the multi-colour (three) fluorescence in situ hybridization (FISH) technique based on the ratio labelling for the detection of monosomy 7 and trisomies 8 and 11 in 13 cases of acute myeloid leukaemia (AML). Two out of the 13 AML cases showed monosomy 7 and two out of the remaining cases exhibited trisomy 8 in interphase nuclei. Three of these results were confirmed by metaphase-FISH study. Trisomy 11 was not found either by the interphase FISH study or in the metaphase FISH study. These results demonstrate the potential power of multi-colour FISH using ratio labelling to produce more fluorescein colour in interphase nuclei for the detection of aneuploidies in leukaemia.en10.1046/j.1365-2257.1997.00186.xinfo:eu-repo/semantics/closedAccessacute myeloid leukaemiafluorescence in situ hybridizationmonosomy 7trisomy 8 and trisomy 11Article19133389146945N/AWOS:A1997WW05800005Q4