Uysal, AhmetDurak, YusufAladağ, Mustafa Onur2020-03-262020-03-262010Uysal, A., Durak, Y., Aladağ, M. O., (2010). Investigation of Mutagenic Effects of Some Plant Growth Regulators on Salmonella/ Microsome Test System. Fresenius Environmental Bulletin, 19(10), 2170-2175.1018-4619https://hdl.handle.net/20.500.12395/25015In this study, beta-naphthoxyacetic acid (BNOA), 4-chlorophenoxyacetic acid (4-CPA) and 2,4-dichlorophenoxyacetic acid (2,4-D) used as plant growth regulators were investigated in order to determine their possible mutagenic activity by Salmonella/microsome test system. Non-toxic doses of BNOA (500, 100, 50, 10, 1 mu g/plaque), 4-CPA (200, 100, 50, 25, 10 mu g/plaque) and 2,4-D (100, 50, 10, 1, 0.1 mu g/plaque) were used in the assays. Assays were carried out through the Salmonella typhimurium TA 98 and TA 100 strains under the conditions both with and without metabolic activation (S9). Numbers of revertants determined in the assays performed with nontoxic doses were compared to those of control plates. Any significant increases in the number of revertants were not observed, in the presence or absence of metabolic activation (S9). Based on the results, it was concluded that BNOA, 4-CPA and 2,4-D were not found to be mutagenic or promutagenic in the Salmonella/microsome test system.eninfo:eu-repo/semantics/openAccessMutagenicitySalmonella typhimuriumPlant growth regulatorsSalmonella / microsome testArticle191021702175WOS:000284394200006N/A