Enhos, SukruDuran, IsmetErdem, SamiBuyukbas, Sadik2020-03-262020-03-2620090022-3492https://dx.doi.org/10.1902/jop.2009.090209https://hdl.handle.net/20.500.12395/23820Background: The aim of this study was to evaluate the periodontal status of patients with iron-deficiency anemia (IDA) and the correlation of changes in serum and gingival crevicular fluid (GCF) ferritin levels after periodontal therapy. Methods: Nineteen female patients with anemic hematologic values were classified as group A, and 20 healthy females with normal hematologic values were classified as group B. After group A was recruited, group B was enrolled with patients who had similar gingival indices as group A. At baseline and the 3-month follow-up visit, clinical periodontal indices and hematologic parameters were recorded, and GCF samples were taken. All patients received an oral hygiene-improvement session followed by scaling, and sites with >4-mm probing depths received root planing. At the 3-month follow-up visit, all measurements and analyses were repeated. Results: During the follow-up period, all clinical indices decreased in both groups (P<0.05), but the gingival index in group A did not change. The GCF ferritin concentration showed statistically significant decreases (P<0.05), but total amounts of ferritin in GCF did not change. No significant correlation was found between serum and GCF ferritin levels. Conclusion: The findings of this study showed that changes in serum ferritin levels did not correlate with the GCF ferritin levels, and IDA was not a direct risk factor for periodontal diseases. J Periodontol 2009;80:1750-1755.en10.1902/jop.2009.090209info:eu-repo/semantics/closedAccessIron deficiency anemiafemalesferritinsperiodontal diseasesArticle80111750175519905931Q1WOS:000271836200009Q1