Kurtoğlu, E.Uğur, A.Gönen, Mustafa SaitKısakol, G.2020-03-262020-03-262003Kurtoğlu, E., Uğur, A., Gönen, M. S., Kısakol, G., (2003). Effect of Lipoprotein Apheresis on Oxidative Stress and Antioxidant Status in Familial Hypercholesterolemic Patients. International Journal of Artificial Organs, 26(11), 1039-1043.0391-3988https://hdl.handle.net/20.500.12395/18429Extracorporeal low-density lipoprotein (LDL) apheresis is an established and highly effective therapy for the patients with familial hypercholesterolemia (FH) not adequately responding to diet and drug therapy alone. This study was designed to measure the effect of lipid apheresis on oxidant and antioxidant status in a patient with FH. The levels of plasma lipid peroxidation were determined as thiobarbituric acid-reactive substances. The activities of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were established in one subject with FH before and after lipid apheresis. The pre- and post lipid apheresis procedures witness a significant decrease in oxidative stress (p<0.05) but the erythrocyte levels of CAT SOD and GPx were unchanged.eninfo:eu-repo/semantics/openAccessFamilial HypercholesterolemiaLipid ApheresisOxidative StressAntioxidantsEffect of Lipoprotein Apheresis on Oxidative Stress and Antioxidant Status in Familial Hypercholesterolemic PatientsArticle26111039104314708833Q3WOS:000187506500010Q3