Tutar L.Tutar Y.2020-03-262020-03-2620080006-3525https://dx.doi.org/10.1002/bip.20881https://hdl.handle.net/20.500.12395/22938Yeast cytosol has two important co-chaperons; Ydj1 and Sis1. Genetic experiments showed that Ydj1 is not essential for viability; however, cells lacking it grow very poorly at 30°C or unable to grow at extreme temperatures. On the other hand, Sis1 is an essential protein and apparently plays a functional role at assembly or disassembly of protein complexes. Stability experiments revealed that only Ydj1-protected Hsp70 proteins can hydrolyze ATP under prolonged stress. © 2007 Wiley Periodicals, Inc.en10.1002/bip.20881info:eu-repo/semantics/closedAccessHsp70Sis1StabilityYdj1Article89317117417985367Q2