Cihangir, NalanGörkemli, HüseyinÖzdemir, SunaAktan, MuradDuman, Selçuk2020-03-262020-03-2620101309-0399https://dx.doi.org/10.5152/jtgga.2010.017https://hdl.handle.net/20.500.12395/25513Objective: In this study, we aimed to evaluate the influence of autologous cumulus oocyte complex (COC) coculture on embryonic development and quality, and investigate the implantation and pregnancy rates after cumulus-aided embryo transfer in the ICSI-ET cycles. Material and Methods: Ninety five consecutive infertile women undergoing their first cycle of IVF teratment were included in the study. The cases were divided into two groups. Group 1 consisted of 48 women undergoing ICSI, along with autologous cumulus embryo coculture and cumulus-aided emryo transfer. Group 2 comprised 47 consecutive patients who consented to undergo ICSI and in whom autologous cumulus embryo coculture and cumulus-aided embryo transfer were not performed. Implantation and pregnancy rates were compared between the two groups. Results: The demographic data and controlled ovarian hyperstimulation parameters were similar in the two groups. The fertilization and cleavage rates were found to be higher in group 1 when compared with group 2 (p=0.03 and 0.001, respectively). There were no statistical significant differences for the implantation and clinical pregnancy rates between the two groups. Conclusion: Usage of autologous COCs as coculture may improve fertilization and cleavage rates. However, cumulus-aided embryo transfer does not produce an increase in implantation and pregnancy rates.tr10.5152/jtgga.2010.017info:eu-repo/semantics/openAccessCocultureCumulus cellsIcsi-embryo transferPregnancy rateArticle113121126Q3