Tonbul, ZekiAltıntepe, LütfullahSözlü, ÇetinYeksan, MehdiYıldız, AlaattinTürk, Süleyman2020-03-262020-03-262003Tonbul, Z., Altıntepe, L., Sözlü, Ç., Yeksan, M., Yıldız, A., Türk, S., (2003). The Association of Peritoneal Transport Properties With 24-hour Blood Pressure Levels in Capd Patients. Peritoneal Dialysis International, 23(1), 46-52.0896-8608https://hdl.handle.net/20.500.12395/18578Objectives: We aimed to investigate the effects of peritoneal transport characteristics on blood pressure (BP) parameters, measured by 24-hour ambulatory blood pressure monitoring (ABPM), and on the development of left ventricular hypertrophy (LVH) in continuous ambulatory peritoneal dialysis (CAPD) patients. Design: Cross-sectional and prospective design. * Setting: Tertiary-care center. Patients: 25 CAPD patients (11 male, 14 female; mean age 47 +/- 14 years) were included. Mean time on CAPD was 22.9 +/- 18 months and all patients had been dialyzed for more than 6 months. The patients were divided into high, high-average, low-average, and low transport groups according to peritoneal equilibration test results. Main Outcome Measures: Daytime and nighttime systolic and diastolic BP and left ventricular mass index among the different peritoneal transport groups; changes in BP parameters before and after increase in ultrafiltration. Results: On 24-hour ABPM records, 13 patients (52%) were found to be hypertensive. Both mean systolic and diastolic BP were significantly increased in high-transporter groups compared to low transporters in both daytime and nighttime BP parameters. Left ventricular mass index was higher in high transporters compared to low transporters, without reaching statistical significance: 160 +/- 23 vs 119 +/- 41 g/m(2), p > 0.05. Following increase in ultrafiltration, mean systolic (145 +/- 13 vs 128 +/- 5 mmHg, p < 0.001) and diastolic (96 +/- 10 vs 81 +/- 3 mmHg, p < 0.001) BP decreased, and BP levels returned to normotensive levels in 6 (46%) of the 13 hypertensive patients, requiring discontinuation of anti hypertensive drugs. Conclusion: Improvement in volume status resulted in a decrease in both daytime and nighttime BR Differences in peritoneal transport properties were associated with the development of hypertension and LVH.eninfo:eu-repo/semantics/openAccessHypertensionLeft ventricularHypertrophyPeritoneal transportPETThe Association of Peritoneal Transport Properties With 24-hour Blood Pressure Levels in Capd PatientsArticle231465212691506WOS:000181646700006Q2