Kaya İslamoğlu, Zeynep Gizem.Altınyazar, Hilmi Cevdet.2020-03-262020-03-262019İslamoğlu, Z. G. K., Altınyazar, H. C. (2019). Effects of Isotretinoin on the Hair Cycle. Journal of Cosmetic Dermatology, 18(2), 647-651.1473-21301473-2165https://dx.doi.org/10.1111/jocd.12800https://hdl.handle.net/20.500.12395/37761Background/ ObjectivesIsotretinoin is a synthetic vitamin A agent that affects all of the pathogenic factors that suppress sebum production and play a role in the formation of acne. It is frequently used in the treatment of moderate-severe acne vulgaris. However, there are some mucocutaneous and systemic side effects that limit the use of isotretinoin. In this study, we aimed to determine the effect of isotretinoin on hair growth parameters. Material and MethodsIsotretinoin treatment at 0.5mg/kg per day dose was started to patients with moderate-severe acne vulgaris, and hair growth parameters were evaluated before treatment and after 3months of treatment. Parameters were measured by Fotofinder dermatoscopy device using the TrichoScan Professional program. ResultsIn the TrichoScan analysis, the total hair count, hair density, percentage of anagen and telogen hair, density, count, and ratio of vellus and terminal hairs in the 0.73 area were calculated. As a result, there were differences in some values between the first analysis and the second analysis. However, these differences were not statistically significant. ConclusionOur study was based on the mucocutaneous side effects of isotretinoin which are telogen effluvium and thinning hair. Our results support that the drug does not alter hair growth parameters in the short term and when very high doses are not used.en10.1111/jocd.12800info:eu-repo/semantics/openAccessacne vulgarishairisotretinointelogen effluviumTrichoScanArticle18264765130350907Q2WOS:000468038000032Q3