Ozcelik, Egemen.Temel, Farabi.Erdemir, Serkan.Tabakci, Begum.Tabakci, Mustafa.2020-03-262020-03-262019Ozcelik, E., Temel, F., Erdemir, S., Tabakci, B., Tabakci, M. (2019). QCM Sensors Coated with Calix[4]arenes Bearing Sensitive Chiral Moieties for Chiral Discrimination of 1-phenylethylamine Enantiomers. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 95(1), 35-48.1388-31271573-1111https://dx.doi.org/10.1007/s10847-019-00892-zhttps://hdl.handle.net/20.500.12395/38139This article describes the enantiomeric discrimination properties of new chiral calix[4]arene derivatives bearing (S)-/(R)-1-phenylethylamine moieties (5a and 5b, respectively) towards the 1-phenylethylamine enantiomers on QCM surface. Initial experiments demonstrated that the 5b coated QCM sensor was the most effective sensing material for enantiomeric discrimination of (R)-/(S)-1-phenylethylamine by exhibiting much more sensing ability towards (R)-enantiomer than (S)-enantiomer. Sensitivity, detection limit and time constant of the 5b coated QCM sensor has been were calculated as 0.082 Hz/mu M, 2.7 mu M, and 319.2 s, respectively. Additionally, effects of calixarene content and different coating technique on enantiomeric discrimination, and Langmuir and Freundlich isotherms of the sensing results also were studied. As a result, it has been demonstrated that the coating of QCM sensor with a chiral calix[4]arene (5b) having (S)-1-phenylethylamine moieties provides substantially enantiomeric discrimination of 1-phenylethylamine enantiomers.en10.1007/s10847-019-00892-zinfo:eu-repo/semantics/openAccess1-PhenylethylamineOrganic coatingsCalixareneEnantiomeric discriminationQuartz crystal microbalance sensorArticle9513548Q3WOS:000485967900003Q3