Alpaslan, MeteKaralezli, AylinBorazan, MehmetKoktekir, Bengu EkinciMuderrisoglu, Ibrahim Haldun2020-03-262020-03-2620122149-22632149-2271https://hdl.handle.net/20.500.12395/27879Objective: To assess the aortic root function in patients with pseudoexfoliation syndrome (PEXS). Methods: In this case- controlled observational study, aortic root function in 31 PEXS patients (mean age 71 +/- 9 years) and 29 controls of similar ages (mean age 69 9 years) were evaluated by M-mode transthoracic echocardiography. Aortic cross-sectional compliance (CSC), Peterson's elastic modulus (index beta), aortic stiffness index (ASI) and aortic root distensibility (ARD) were calculated by M-mode echocardiography to evaluate the aortic root function. The findings of two groups of patients were compared by Mann-Whitney U test. Results: The CSC and ARD were significantly decreased in patients with PEXS. The CSC was 12.2 +/- 6.3 cm(2)/mmHg in patients with PEXS and 17.5 +/- 11.6 cm(2)/mmHg in the control group (p=0.015). The ARD was 1.56 +/- 0.80 cm(2)/dyne in patients with PEXS and 2.23 +/- 1.48 cm(2)/dyne in the control group (p=0.021). The other two indices of aortic root function were not significantly different between the two groups. Conclusion: Aortic root function decreases in patients with PEXS. PEXS may be regarded as a risk factor for cardiovascular and cerebrovascular events. (Anadolu Kardiyol Derg 2012; 12:483-7)eninfo:eu-repo/semantics/openAccessEchocardiographyaortic root functionaortapseudoexfoliation syndromeArticle12648348722677407Q3WOS:000308575800007N/A