Akceylan, EzgiSahin, OzlemYilmaz, Mustafa2020-03-262020-03-2620141388-31271573-1111https://dx.doi.org/10.1007/s10847-013-0332-zhttps://hdl.handle.net/20.500.12395/30918Candida rugosa lipase immobilized on calix[4] arene carboxylic acid-grafted magnetic nanoparticles using a sol-gel encapsulation technique was tested for activity, which was assessed both in the enantioselective hydrolysis of racemic Naproxen methyl ester and that of p-nitrophenylpalmitate. It has also been noticed that, compared to the free enzyme (E = 137) with an ee value of [98 %, S-Naproxen calix[4] arene carboxylic acid-grafted magnetic nanoparticles based on encapsulated lipase (Calix-1-MN and Calix-2-MN) offer excellent enantioselectivity (E = 373 and E = 381). Moreover, the results indicated that after the fifth reuse in the enantioselective reaction, the encapsulated lipase (Calix-2-MN) still retained about 43 % of its conversion power.en10.1007/s10847-013-0332-zinfo:eu-repo/semantics/closedAccessLipaseEnantioselectivityCalix[4]areneMagnetic nanoparticlesArticle7901.02.2020113123Q3WOS:000339273600010Q2