Solak, İbrahimMarakoğlu, KamilePekgör, SelmaKargın, Nisa ÇetinAlataş, NecatEryılmaz, Mehmet Ali2020-03-262020-03-262018Solak, İ., Marakoglu, K., Pekgor, S., Kargin, N. C., Alatas, N., Eryilmaz, M. A. (2018). Nasal Mucociliary Activity Changes in Smokers. Konuralp Tıp Dergisi, 10(3), 269-275.1309-3878https://dx.doi.org/10.18521/ktd.344288https://hdl.handle.net/20.500.12395/36792Objective: Nasal mucociliary activity, which is a good indicator of nasal mucosal function, is one of the most important defense mechanisms of the body. The aim of the present study is to investigate the effect of smoking and cigarette consumption on nasal mucociliary activity per se by singling out other factors affecting nasal mucociliary activity. Methods: One hundred ninety seven patients aged 18-55 years, one hundred twenty three smokers (case group) and seventy four non-smokers (control group), were included in the present study. Saccharin transfer time (STT) test, CO measurement, Fagerstrom Test for Nicotine Dependence, and a questionnaire including smoking characteristics were applied to all participants. Results: No statistically significant difference was determined between the case and control group in terms of age and body mass index parameters affecting mucociliary activity. In the present study, a statistically significant difference was determined in the mucociliary transfer time between the case and the control group. Moreover, a positive correlation between saccharin transfer time (STT) and number of cigarettes smoked per day, STT and package-year, STT and total smoking years was also determined. Conclusions: In conclusion, smoking has been in the present study determined to deteriorate nasal mucociliary system with a direct proportion to the amount and total duration of smoking.en10.18521/ktd.344288info:eu-repo/semantics/openAccessSmokingSaccharin Transfer TimeMucociliary ActivityArticle103269275#YOKWOS:000450536200003N/A