Pekin, Aybike TazegulKerimoglu, Ozlem SecilmisKebapcilar, Ayse GulYilmaz, Setenay ArzuBenzer, NilgunCelik, Cetin2020-03-262020-03-2620140932-00671432-0711https://dx.doi.org/10.1007/s00404-014-3237-1https://hdl.handle.net/20.500.12395/30719The aim of our study was to examine the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) treatment on depressive symptoms, changes in bleeding patterns, and quality of life (QoL) among premenopausal women in our clinic. We recruited 120 premenopausal women, aged 18-50 years, who had sought care in the previous year for menorrhagia. LNG-IUS was inserted into eligible patients after the relevant evaluations. Both questionnaires were administered at time of the initial screening before and 6 months after insertion of the LNG-IUS. All patients completed the 36-item Short-Form Health Survey (SF-36) for QoL and Beck's Depression Inventory for depressive symptoms. At the 6-month follow-up visit, the pictorial blood assessment chart score (PBAC) considerably decreased (p < 0.001). For SF-36 scores, physical functioning, physical role limitations, emotional role limitations, bodily pain, vitality, and mental health scores improved significantly after treatment (p < 0.001). Depression scores showed no significant difference from baseline to 6 months (p = 0.375). The LNG-IUS for the treatment of menorrhagia increases the QoL, and depression scores did not increase significantly in 6 months.en10.1007/s00404-014-3237-1info:eu-repo/semantics/closedAccessLevonorgestrel-releasing intrauterine system (LNG-IUS)MenorrhagiaQuality of lifeArticle290350751124748280Q2WOS:000340518300020Q3