Ercan, MüjganCaniklioğlu, AyşenOğuz, Esra FıratYücel, ÇiğdemÖzcan, MehmetYılmaz, Fatma MeriçAbuşoğlu, Sedat2020-03-262020-03-262019Ercan, M., Caniklioğlu, A., Oğuz, E. F., Yücel, Ç., Özcan, M., Yılmaz, F. M., Abuşoğlu, S. (2019). The effect of measurement uncertainty for HOMA-IR in assessment of insulin resistance. Medicine Science, 8(1), 32-36.2147-06342147-0634https://dx.doi.org/10.5455/medscience.2018.07.8905http://www.trdizin.gov.tr/publication/paper/detail/TXpBNE1qWXlNZz09https://hdl.handle.net/20.500.12395/37369In this study, it is aimed to estimate not just the uncertainty measurement for the parameters of glucose and insulin having role when calculating HOMA-IR, but also true positiveness and negativeness in terms of cut-off values. The evaluation of the acceptability of the uncertainty value was also among the goals of the study. The uncertainty measurement for glucose and insulin is calculated as uncertainty measurement of HOMA-IR based on Eurochem/CITAC Guide CG 4. The uncertainty measurement for glucose and insulin was estimated as 3.83% and 4.16%, respectively. The measurement uncertainty for the calculated test HOMA-IR was calculated with cut-off values as 27% (0.27). Based on the cut-off value for HOMA-IR of 2.5%, IR() and IR(-) patients were 155 and 265, respectively. If the uncertainty measurement for HOMA-IR was added to its calculation, the cut-off value was detected as 2.23-2.77%. We reported the measurement uncertainty of the calculated test HOMA-IR at 95 % CI as 0.27 between 2.23 - 2.77. Especially for the tests used for screening; determination of cut-off values as a range including measurement uncertainty instead of a single value will be more suitable. No data is found in the literature for the calculated test HOMA-IR up to date.en10.5455/medscience.2018.07.8905info:eu-repo/semantics/openAccessAcil TıpAdli TıpAlerjiAnatomi ve MorfolojiAndrolojiAnesteziBiyofizikBiyokimya ve Moleküler BiyolojiBiyolojiBiyoteknoloji ve Uygulamalı MikrobiyolojiCerrahiDermatolojiEndokrinoloji ve MetabolizmaEnfeksiyon HastalıklarıFizyolojiGastroenteroloji ve HepatolojiGenel ve Dahili TıpGeriatri ve GerontolojiGöz HastalıklarıHalk ve Çevre SağlığıHematolojiHücre BiyolojisiİmmünolojiKadın Hastalıkları ve DoğumKalp ve Kalp Damar SistemiKlinik NörolojiKulakBurunBoğazMikrobiyolojiNörolojik BilimlerOdyoloji ve Konuşma-Dil PatolojisiOnkolojiOrtopediPatolojiPediatriPeriferik Damar HastalıklarıPsikiyatriRadyolojiNükleer TıpTıbbi GörüntülemeRehabilitasyonRomatolojiSağlık Bilimleri ve HizmetleriSolunum SistemiSpor BilimleriTamamlayıcı ve Entegre TıpTemel Sağlık HizmetleriTıbbi Araştırmalar DeneyselTıbbi EtikTıbbi İnformatikTıbbi Laboratuar TeknolojisiTransplantasyonTropik TıpÜroloji ve NefrolojiYoğun BakımTıpArticle813236