Sur, EmrahDonmez, Hasan HuseyinBoydak, MuratAtaman, Mehmet Bozkurt2020-03-262020-03-2620121537-744Xhttps://dx.doi.org/10.1100/2012/632945https://hdl.handle.net/20.500.12395/27982This study was aimed to determine the effects of the glucomannan added to aflatoxin- (AF-) contaminated diet on the sacculus rotundus and peripheral blood lymphocytes of New Zealand rabbits by histological and enzyme histochemical methods. Twenty-four adult rabbits of both sexes were divided into four equal groups, namely, as control, glucomannan 0.2 g/day, AF 125 mu g/kg/day, and glucomannan combined with AF. The animals in all groups were treated for 12 weeks by the above-mentioned diet. When compared to control, AF-treatment caused significant decrease in alpha-naphthyl acetate esterase- (ANAE-) positive peripheral blood lymphocyte (PBL) percentages. The addition of the glucomannan to AFcontaining diet recovered the adverse effects of AF on sacculus rotundus and increased the ANAE-positive PBL counts. These results suggested that glucomannan was effective against the negative effects of AF in rabbits.en10.1100/2012/632945info:eu-repo/semantics/openAccessArticle22645440Q2WOS:000307067100001Q1