Özmen, S.Ökeşli, S.İlhan, N.Akhan, G.Otelcioğlu, S.Ünal, F.2020-03-262020-03-261992Özmen, S., Ökeşli, S., İlhan, N., Akhan, G., Otelcioğlu, S., Ünal, F., (1992). EEG Findings in Etomidate Anaesthesia. Türk Anesteziyoloji ve Reanimasyon, 20(1), 27-32.1016-5150https://hdl.handle.net/20.500.12395/16153This study included 30 volunteer cases (19 male, 11 female) in ASA-I group with normal electroancephalographic findings. All cases divided in 3 groups randomly and 45 minutessd prior to administration of etomidate, first group was premedicated with 0.5 mg Atropine, second group with 0.5 mg Atropine and 10 mg Diazepam and third group with 0.5 mg Atropine and 01. mg Fentanyl. Induction has been succeeded by IV 0.4 mg/kg etomidate. In order to maintain anaesthesia 0.1 mg/kg etomidate was administered intravenously at 5th minute and EEG was obtained for 15 mintures after first dosage of etomidate. The EEG findings of etomidate anaesthesia and the relation of myoclonia (the main side effect) with CNS was evaluated by EEG records. EEG findings were not affected with premedication methods and no correlation between myoclonia and EEG signs was established. However, myoclonia was decreased significantly in patients who received Fentanyl as premedication. Instead of the irregular alpha and fast activities were observed on control EEG recordings in patients anaesthetised with etomidate. The sharp waves and the suppression burst activities appeared in some cases. In conclusion attention must be paid during etomidate anaesthesia in epileptic patients or it should be avoided using etomidate in patients who has a history of epilepsy because of the possibility of provocating the seizures.trinfo:eu-repo/semantics/closedAccessArticle2012732N/A