Balcı, OsmanMahmoud, Alaa S.Özdemir, SunaAcar, Ali2020-03-262020-03-262010Balcı, O., Mahmoud, A. S., Özdemir, S., Acar, A., (2010). Induction of Labor with Vaginal Misoprostol Plus Oxytocin Versus Oxytocin Alone. International Journal of Gynecology & Obstetrics, (110), 64-67. Doi: 10.1016/j.ijgo.2010.02.0040020-72921879-3479https://dx.doi.org/10.1016/j.ijgo.2010.02.004https://hdl.handle.net/20.500.12395/24999Objective: To compare the effect of an oxytocin infusion alone or preceded by an intravaginal application of misoprostol for labor induction in women with term pregnancies and a low Bishop score. Methods: This study randomized 100 multiparous women with singleton pregnancies over 38 weeks and a Bishop score less than 6 to receive either a single 50-mu g dose of misoprostol intravaginally 3 hours before initiation of the oxytocin infusion or only an oxytocin infusion. The time from induction to delivery, the route of delivery, and maternal and fetal outcomes were analyzed. Results: The mean time from induction to delivery was 9.36 +/- 1.97 hours in the misoprostol plus oxytocin group and 11.08 +/- 3.23 in the oxytocin alone group (P=0.002). The rates of vaginal delivery, 1- and 5-minute Agpar scores, placental abruption, and postpartum hemorrhage were similar between the 2 groups, as were the rates of admission to the neonatal intensive care unit. There were no cases of perinatal asphyxia. Conclusion: A 50-mu g intravaginal application of misoprostol before starting the oxytocin infusion is a more effective method of labor induction than an oxytocin infusion alone for our study population.en10.1016/j.ijgo.2010.02.004info:eu-repo/semantics/openAccessInduction of laborMisoprostolOxytocinArticle110646720347088Q1WOS:000279568900016Q2