Kibar, M.Tuna, B.Kısadere, İ.Güzelbekteş, H.2020-03-262020-03-262019Kibar, M. E., Tuna, B., Kısadere, İ., Güzelbekteş, H. (2019). Comparison Of Instilled Lidocaine and Procaine Effects on Pain Relief in Dogs Undergoing Elective Ovariohysterectomy. Israel Journal of Veterinary Medicine, 74(3), 148-154.0334-91522304-8859https://hdl.handle.net/20.500.12395/37614The aim of the present study was to compare the analgesic efficacy of instilled intra-peritoneal lidocaine and procaine during the perioperative and the postoperative periods in dogs undergoing elective ovariohysterectomy (OVH). Twenty-four sexually intact female dogs were referred for OVH. Following the laparotomv procedure the L group received intraperironeal instillation of 3.5 mg/kg of 0.2% lidocaine. The therapeutic agent was administreted over the area of ovaries, broad ligament, and uterine stump. It was injected using a syringe and needle (23 G). The P group administered intraperitoneal instillation of 3.5 mg/kg of 0.2% procaine and the control group received 1.75 ml/kg of intraperitoneal saline in a similar fashion. Groups L and P had significantly lower Glascow Composite Measure Pain Scale scores (CMPS-SF) than the control group at the 0.5, 1,2, 3, 8, and 24 hour postoperative periods. In conclusion, administerstration of intraperitoneal installation of lidocaine and procaine were shown to provide a milady significant effect in reducing intraoperative and postoperative pain and biochemical stress responses within 3 hours of surgery.eninfo:eu-repo/semantics/openAccessLidocaineOvaxiohysterectornyPainProcaineArticle743148154Q3WOS:000487704600008Q4