Melucci, DoraLocatelli, MarcelloDe Laurentiis, FrancescoZengin, GökhanLocatelli, Clinio2020-03-262020-03-2620181570-18081875-628Xhttps://dx.doi.org/10.2174/1570180814666170412124634https://hdl.handle.net/20.500.12395/36669Background: The work describes the voltammetric determination of mercury(II), copper(II), lead(II), cadmium(II), zinc(II) by square wave anodic stripping voltammetry (SWASV) in herbal medicines. Methods: The voltammetric measurements were carried out using a conventional three electrode cell and two working electrodes, a gold electrode (GE) and a stationary hanging mercury drop electrode (HMDE). The analytical procedure was verified on the standard reference materials Spinach Leaves NIST-SRM 1570a, Tomato Leaves NIST-SRM 1573a and Apple Leaves NIST-SRM 1515. For all the elements, precision as repeatability, expressed as relative standard deviation (s(r)) was of the order of 4-6 %, while authenticity, expressed as relative error (e) was generally of the order of 5-8 %. Once set up on the standard reference materials, the analytical procedure was applied to commercial herbal medicine samples, and a critical comparison with spectroscopic measurements was done to evaluate the analytical performance. Results and Conclusion: Results are also processed by Principal Components Analysis (PCA), which provides very easy-to-read graphic outputs evidencing the influence of herbs prewashing on the content of risky elements. The correlation matrix is also obtained, allowing to study correlation between elements or methods.en10.2174/1570180814666170412124634info:eu-repo/semantics/closedAccessHerbal medicinestoxic metalsvoltammetryinterferencesspectroscopyPCAArticle153270280Q3WOS:000423791700009Q4