Altunhan, HüseyinAnnagür, AliTarakcı, NuriyeKonak, MuratErtuğrul, SabahattinÖrs, Rahmi2020-03-262020-03-2620161476-70581476-4954https://dx.doi.org/10.3109/14767058.2015.1045864https://hdl.handle.net/20.500.12395/33629Objectives: The purpose of this study was to compare the efficacy and safety of two different catheterization techniques of exchange transfusion (ET) used in the therapy of newborn jaundice: fully automated two-way ET technique and the classical one-way ET.Patients and methods: The study included babies at gestational age of >34 weeks. In total, 107 ETs were performed on 86 babies. Totally, the umbilical vein (UV) group included 54 babies having undergone 69 ETs and the UV/UA group included 32 babies having undergone 38 ETs.Results: The declines in bilirubin levels right after ET (p=0.018) and 8h after ET (p=0.014) were higher in the fully automated UV/UA technique than in the classical UV technique. Furthermore, the duration of intensive phototherapy following ET was shorter in the UV/UA method than in the UV method (p=0.003). There was no difference between the two methods in terms of ET-associated complications (p=0.927).Conclusions: In neonatal hyperbilirubinemia, ET with fully automated UV/UA technique is more efficient than the classical ET technique, causing no additional side-effects. It is also more physiological than the classical technique, since it minimizes the fluctuations in the blood volume and intravascular pressure during ET.en10.3109/14767058.2015.1045864info:eu-repo/semantics/closedAccessAutomated exchange transfusionexchange transfusionneonatal hyperbilirubinemiaumbilical arteryumbilical veinArticle2981274127826030680Q2WOS:000368718700015Q3