Uysal, AhmetGunes, ErdoganArslan, EmineDurak, Yusuf2020-03-262020-03-2620181018-46191610-2304https://hdl.handle.net/20.500.12395/36389In this study, 97 Escherichia coli strains isolated from urinary tract infections were evaluated in terms of phenotypic diversity, susceptibility to sixteen antibiotics, and extended spectrum of beta lactamase (ESBL) characteristics. The bacteriophage interactions was used to identify the relations of the E.coli isolates. Results showed that 21 of the 76 typable strains revealed 19 different phage types. Phage types of 21 strains could not be determined. Antibiotic susceptibility tests, performed against sixteen antibiotics, showed that although the isolates revealed 44 different types of resistance profiles, the strains showed the greatest resistance to cephalothin (54.6%), followed by tetracycline (53.6%), nalidixic acid (44.3%), and aztreonam and ofloxacin (29.8%). There was no resistance to amikacin and meropenem, and all strains were susceptible to meropenem. ESBL detection conducted by double disc synergy and multiplex polymerase chain reaction methods showed that 13 of 97 (13.4%) strains were ESBL-producing. Of the 13 ESBL-producing isolates, two carried bla(CTX-M), six bla(TEM), five bla(OXA), and one bla(TEM) and bla(SHV) at same time. We concluded that lytic phages could not be successful for typing the strains phenotypically. The monitoring of antimicrobial resistance levels and antimicrobial usage in humans should be an integral part of the prevention and control of antimicrobial resistance.eninfo:eu-repo/semantics/closedAccessUropathogenic E. coliphage typingantibiotic resistanceESBL genesmultiplex PCRArticle271402414N/AWOS:000426337900050Q4