Yazıcı, ZübeydeKaya, YalçınBaltacı, Abdülkerim KasımMoğulkoç, RasimÖztekin, Esma2020-03-262020-03-2620080172-780Xhttps://hdl.handle.net/20.500.12395/22715OBJECTIVES: The aim of this study was to investigate the effects of intraperitoneal (IP) boron administration on leptin and lactate levels in swimming exercise in ovariectomized rats. METHODS: Eighty adult female rats were equally allocated into 8 groups. Group 1; Control, Group 2; exercise control, Group 3; ovariectomized control, Group 4; Boron control (2 mg/kg/day), Group 5; ovariectomized plus exercise, Group 6; exercise plus IP boron, Group 7; ovariectomized and exercise group plus IP boron, Group 8; ovariectomized plus boron. RESULTS: Leptin levels in Group I were higher than those in Groups 2, 3 and 4 and lower than those in groups 5, 6, 7 and 8 (p<0.01). Leptin levels were higher in Group 3 than in Groups 2 and 4 and significantly lower than in all other groups (p<0.01). Lactate levels in Groups 2 and 4 were higher than those in all other groups (p<0.01). Lactate levels were significantly lower in Groups 1, 3, 5 and 8 than in all other groups (p<0.01). Lactate levels in Groups 6 and 7 were significantly lower than those in Groups 2 and 4 (p<0.01) and higher than those in groups 1, 3 and 5 (P<0.01). CONCLUSION: The present findings demonstrate that ovariectomy and acute swimming exercise in rats led to a significant decrease in leptin levels and a significant increase in lactate levels and that boron administration prevented the increased in circulating lactate concentration induced by swimming exercise.eninfo:eu-repo/semantics/closedAccessacute swimming exerciseovariectomyboron administrationlactate and leptinArticle29117317718283241Q4WOS:000254164800034Q4