Çelik, GülperiYöntem, MustafaCilo, MustafaBilge, MuratMehmetoğlu, İdrisÜnaldı, Mustafa2020-03-262020-03-262012Çelik, G., Yöntem, M., Cilo, M., Bilge, M., Mehmetoğlu, İ., Ünaldı, M., (2012). The Relationship Between Glutathione Peroxidase and Bioimpedance Parameters in Nondiabetic Hemodialysis Patients. Hemodialysis International, 16(2), 274-281. DOI:10.1111/j.1542-4758.2011.00628.x1492-7535https://dx.doi.org/10.1111/j.1542-4758.2011.00628.xhttps://hdl.handle.net/20.500.12395/28553There is growing evidence from experimental and clinical studies that oxidative stress is involved in the pathogenesis of malnutrition. This cross-sectional study aimed to investigate the relationship between glutathione peroxidase (GPx) levels as a marker of antioxidant status and the nutritional status assessed by bioimpedance analysis (BIA). Ninety-seven nondiabetic stable outpatient uremic adults undergoing chronic hemodialysis (HD) were recruited for this study. Impedance measurements were performed using a multifrequency bioelectrical impedance analyzer after dialysis. GPx levels correlated with intracellular water (ICW) (r?=?0.341, P?=?0.011), ICW/total body weight (r?=?0.320, P?=?0.017), lean body mass (r?=?0.300, P?=?0.026) and total body cell mass (r?=?0.339, P?=?0.011). When patients were divided into two groups according to mean GPx levels (83.9 U/gr hemoglobin), the patients with higher GPx (GPx?>?83.9?U/gr hemoglobin) had higher albumin (P?=?0.038), lean body mass (P?=?0.026), ICW (P?=?0.011), and total body cell mass (P?=?0.011) compared with those with lower GPx (GPx?=?83.9 U/gr hemoglobin). Furthermore, in the patients with higher GPx, body fat; extracellular water/total body water; illness marker and body fat mass index were lower than other group. In conclusion, our results reveal correlation indicating a relationship between antioxidant status (as measured by GPx) and nutritional status as assessed by BIA in nondiabetic HD patients.en10.1111/j.1542-4758.2011.00628.xinfo:eu-repo/semantics/openAccessHemodialysisGlutathione PeroxidaseMalnutritionBody Cell MassIntracellular WaterArticle16227428122099743Q3WOS:000302612000012Q3