Cicekcibasi, Aynur E.Celik, IlhamiSalbacak, AhmetOzkan, YaseminOkudan, NilselBuyukmumcu, Mustafa2020-03-262020-03-2620080379-5284https://hdl.handle.net/20.500.12395/22317Objectives: To determine the effects of very weak, extremely low frequency (50 Hz) electromagnetic field (ELF-EMF) on the relative spleen weight, lymphoid organ histology, peripheral blood leukocyte and alpha-naphthyl acetate esterase positive (ANAE-positive) lymphocyte percentages of the mouse. Methods: The study was carried out in Scientific Research and Application Center of Selcuk University, Konya, Turkey in 2005. A total of 120 Swiss albino mice were divided into 6 groups (20 in each group). The experimental animals were exposed to 1, 2, 3, 4 and 5 mu T flux intensities (rms) of EMF at 50 Hz for 40 days. Results: In the exposure groups with 20 animals, the body weight (BW) increased gradually in higher field intensities and reached at peak level in the 4 mu T, and then slightly decreased. The relative spleen weight (% of the BW) was not affected. The ELF-EMF treatment did not cause any significant change in lymphocyte, monocyte and ANAE-positive lymphocyte ratios, whereas percentages of neutrophils and basophiles changed non-linearly. Any change in the lymphoid organ histology, which is attributable to the field effect, was not observed in the exposure groups. Conclusion: Extremely low frequency-EMF exposure with the flux intensities between 1-5 mu T for 40 days did not cause any effect on the relative spleen weight, lymphoid organ histology, leukocyte and ANAE-positive lymphocyte percentages of the mouse.eninfo:eu-repo/semantics/openAccessArticle291364118176671WOS:000252791600005Q4