Topal, AhmetCelik, Jale BengiTekin, AhmetYuceaktas, AliOtelcioglu, Seref2020-03-262020-03-2620111530-4515https://dx.doi.org/10.1097/SLE.0b013e3182397863https://hdl.handle.net/20.500.12395/26925Objective: The aim was to determine the influence of the pneumoperitoneum at 10, 13, and 16mm Hg on thromboelastograph (TEG) in laparoscopic cholecystectomy. Methods: Sixty patients were randomly allocated to 3 groups. The abdomen was insufflated with carbon dioxide to 10mm Hg (group 1), 13mm Hg (group 2), and 16mm Hg (group 3) intra-abdominal pressures. We evaluated changes in the TEG values [ reaction time (R), maximum amplitude (MA), alpha-angle, K time] preoperatively, intraoperatively, and postoperatively. Results: In the postoperative 24th hour, the R-value was significantly lower in group 3 than that in group 1 and group 2 (P< 0.05). We found increased values of MA intraoperative 30th minute and postoperative 24th hour in group 3 with respect to group 1 (P< 0.05) and postoperative 24th hour, and the MA value in group 3 was significantly higher than those of group 2 (P< 0.05). In group 3, the alpha-angle was significantly higher than that of group 1 and group 2 at intraoperative 30th minute and postoperative 24th hour (P< 0.05). In postoperative 24th hour, the K-value was significantly lower in group 3 than in group 2 and group 1 (P< 0.05). Conclusions: Laparoscopy with pneumoperitoneum at pressures of 10 and 13mm Hg did not alter the TEG values and low intra-abdominal pressure must be used for peritoneal insufflation.en10.1097/SLE.0b013e3182397863info:eu-repo/semantics/closedAccesslaparoscopycholecystectomythromboelastographArticle21643443822146167Q2WOS:000298143700026Q3