Ozturk, ABaltaci, AKMogulkoc, ROztekin, EKul, A2020-03-262020-03-2620050172-780Xhttps://hdl.handle.net/20.500.12395/19925AIM: The aim of this study was to investigate how zinc-deficiency and testosterone supplementation, both in combination and individually, affect plasma LH, FSH and leptin levels in castrated rats. DESIGN: Group 1, Control Group. Group 2, Castration Group. Group 3, Testosterone Group. Group 4, Zinc-deficient Group. Group 5, Testosterone, Zinc-deficient Group. Group 6, Zinc-deficient, Castration Group. Group 7, Testosterone, Castration Group. Group 8, Zinc-deficient, Testosterone, Castration Group. MEASUREMENTS: Plasma zinc, leptin, LH, FSH, free and total testosterone levels were measured. RESULTS: Group 2 had the highest levels of leptin and LH, besides having the highest FSH levels together with Group 6 (p < 0.01). Groups 5 and 8 had the lowest leptin levels (p < 0.01). Leptin levels in Groups 4 and 7 were higher than those in Groups 5 and 8, but lower than those in all other groups (p < 0.01). LH levels in Group 4 were not different than those in Groups 3, 5 and 8, but significantly lower than those in all other groups (p < 0.01). Free and total testosterone levels were higher in Group 4 than in castration groups that were not supplemented testosterone, but were lower in the former than in all others (p < 0.01). CONCLUSION: Plasma LH may be more effective than testosterone on plasma leptin and zinc can be an important mediator of the effect LH exercises on leptin.eninfo:eu-repo/semantics/openAccesscastrationtestosterone supplementationzinc deficiencyleptinLHFSHtestosteroneArticle26554855416264402Q4WOS:000234612300020Q4