Oğuz, H.Hadimli, Hasan HüseyinKurtoğlu, VarolErganiş, Osman2020-03-262020-03-262003Oğuz, H., Hadimli, H. H., Kurtoğlu, V., Erganiş, O., (2003). Evaluation of Humoral Immunity of Broilers During Chronic Aflatoxin (50 and 100 Ppb) and Clinoptilolite Exposure. Revue De Medecine Veterinaire, 154(7), 483-486.0035-1555https://hdl.handle.net/20.500.12395/18474In this study, total aflatoxin, (AF) and a natural zeolite (clinoptilolite; CLI) were added to the broiler feed and development of humoral immunity against Infectious Bronchitis (IB) and Newcastle Disease (ND) was evaluated. A total of 576 1-d-old Ross broiler chicks (96 per each) were housed in six treatment groups [Control, CLI,(15 g/kg diet), 50 ppb AF, 50 ppb,AF plus CLI, 100 ppb AF, 100 ppb AF plus CLI] and fed for 42 days. Compared to controls, the antibody titres of IB were determined significantly lower (p < 0.05) in 50 and 100 ppb AF fed chicks from 20 to 42 days of age. The ND titres were also significantly lower (p < 0.05) in 100 ppb AF fed chicks, while no significant differences were seen in 50 ppb AF group compared to controls (p > 0.05). The addition of CLI to the AF-containing diets (50 and 100 ppb) significantly ameliorated (p < 0.05) the adverse effect of AF on humoral immunity. The single addition of CLI to the AF-free diet had no adverse effects in chicks, except the IB titres on 42nd day.eninfo:eu-repo/semantics/openAccessAflatoxinBroilerHumoral immunityZeoliteClinoptilolitePreventionArticle1547483486Q3WOS:000184774600005Q4