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    Processing speed may improve earlier than response inhibition/ interferens in children with ADHD-combined type receiving methylphenidate: a single-center study
    (TAYLOR & FRANCIS LTD, 2019) Çetin, Fatih Hilmi.; Güler, Hasan Ali.; Ersoy, Sevde Afife.; Türkoğlu, Serhat.
    OBJECTIVES: The aim of this study was to determine the order of improvement in response inhibition, interference capacity, and processing speed in the Stroop test after starting methylphenidate treatment in children with ADHD. METHODS: This study included a total of 52 children aged 7-16 years who were diagnosed with combined-type ADHD for the first time and who began to use methylphenidate treatment. The Stroop test was applied to each subject at least 3 times (before treatment and at the first and second months of treatment) in the follow-up visits. RESULTS: The participants completed the fifth section of the Stroop test at a median duration of42.09 sec (quartiles: 35.58-54.0 sec) before treatment, while the median duration was 34.49 sec (quartiles: 27.43-34.48 sec) at the first month of treatment and 32.18 sec (quartiles: 26.97-32.18 sec) at the second month of treatment. The task completion duration showed a statistically significant improvement from the first month of treatment (p < 0.001). When the participants were compared in terms of the number of errors and corrections they made in the fifth section of the Stroop test, there was no significant difference between pretreatment measurements and post-treatment first month measurements (p > 0.05). The number of errors and corrections were statistically significantly lower in the second month of treatment compared to pretreatment and 1st mont of the treatment (p < 0.05). CONCLUSIONS: This study demonstrated that processing speed, response inhibition, and interference capacity assessed by the Stroop test improved with methylphenidate treatment in children with ADHD. This study is the first study to show that these improvements occur in a certain order over time.
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    Romatizmal kalp hastalığı olan çocuk ve ergenlerde psikiyatrik problemler ve bunları etkileyen faktörler: Bir ön çalışma
    (GALENOS YAYINCILIK, 2019) Uytun, Merve Cikili.; Çelik, Serkan Fazlı.; Çetin, Fatih Hilmi.; Babadağı, Zehra.; Uytun, Salih.
    INTRODUCTION: We aimed to evaluate the psychiatric symptoms in addition to quality of life in children and adolescents with rheumatic heart disease, and to determine which factors contribute to psychiatric problems of them. MATERIALS and METHODS: A total of 25 children and adolescents with rheumatic heart disease, additionally, 25 children and adolescents with typical developing controls aged 6-16 years old were included. Kiddie-Schedule for Affective Disorders and Schizophrenia, (present and life time version - K-SADS-PL) was applied to parents of all of the children and adolescents, and Child Depression Inventory, The Spielberger State-Trait Anxiety Inventory for children KINDLR Questionnaire for Measuring Health-Related Quality of Life in Children and Adolescents were applied to all of the children and adolescents. Assessment for mothers, Beck Depression Inventory, Beck Anxiety Inventory and Five Factor Personality Inventory were used. RESULTS: We found higher anxiety scores and increased anxiety disorder diagnosis among children and adolescents with rheumatic heart disease (p<0.05). Mothers' anxiety scores, depression scores, and personality traits are associated with KINDL subscales, and neuroticism scores are also associated with Child Depression Inventory scores. In addition, presence of psychiatric disorder was predicted by Beck anxiety scores. CONCLUSIONS: Our results suggest that psychiatric evalution is important in the treatment of children and adolescents and their parents with rheumatic heart disease.