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Öğe Case presentation: Approach to acute rheumatic fever patient with hepatotoxicity due to acetylsalicylic acid [Bir olgu eşliğinde asetilsalisilik asite bağlı karaciğer toksisitesi gelişen akut romatizmal ateş hastasına yaklaşım](Galenos Yayincilik,, 2017) Güvenç O.; Çimen D.; Aslan E.; Emiroğlu H.; Arslan D.; Oran B.Treatment with acetylsalicylic acid is the first choice for arthritis and mild carditis of acute rheumatic fever which is a common disease in our country. There may be many adverse reactions during treatment. 10 year-old male patient diagnosed as acute rheumatic fever had hepatotoxicity due to acetylsalicylic acid therapy. This clinic manifestation has the possibility that can be seen always in pediatric cardiology practice.This case is presented due to limited literature on the treatment of patients with hepatotoxicity. © 2017, Galenos Yayincilik. All rights reserved.Öğe Evaluation of cardiac functions of infants of diabetic mothers using tissue Doppler echocardiography [Diyabetik anne bebeklerinde kalp işlevlerinin doku Doppler ekokardiyografi ile de?erlendirilmesi](Kare Publishing, 2014) Çimen D.; Karaaslan S.Aim: Transient cardiac hypertrophy occurs in infants of diabetic mothers. The effect of this state on cardiac functions was investigated with a casecontrol study using tissue Doppler technique. Material and Methods: In this study, right and left ventricle systolic and diastolic functions of 45 term babies of diabetic mothers and 50 healthy term newborns were examined using tissue Doppler echocardiography. Results: The septum was found to be thick in 16 (36%) of the babies of diabetic mothers. Both the left and right ventricle myocardial velocities were found to be lower in the babies of diabetic mothers compared to the control group. In our study, the Em/Am ratio was found to be below one only in the babies of diabetic mothers in the left ventricle in contrast to the control group. In addition, the Em/Am ratio in the septum and right ventricle was found to be below one both in the babies of diabetic mothers (group 1, 2) and control group. The calculated Tei index was found to be higher in the babies of diabetic mothers who had a thicker interventricular septum compared to the control group. Conclusion: Interventricular septal thickening in babies of diabetic mothers disrupt the diastolic function of both ventricles. This can be demonstrated by tissue Doppler echocardiography. These results show that diastolic function is disrupted in both ventricles in babies of diabetic mothers and only in the right ventricle in healthy babies. It was thought that this could be explained by right ventricular dysfunction arising from physiological pulmonary hypertension in the neonatal period. Subclinical right and left ventricular diastolic dysfunctions which we found by tissue Doppler indicate that babies of diabetic mothers especially with a thick septum should be closely monitored. © 2014 by Turkish Pediatric Association.Öğe A giant aortic root aneurysm determined by chance: Original image(Turkiye Klinikleri, 2014) Arslan D.; Güvenç O.; Çimen D.; Görmüs N.; Oran B.; Sarigül A.[Abstract not Available]Öğe A rare disease: Mucopolysaccharidosis type 6 and cardiac involvement: Case Report [Nadir Görölen Bir Hastalik: Mukopolisakkaridoz Tip 6 ve Kalp Tutulumu](Turkiye Klinikleri, 2015) Gövenç O.; Çimen D.; Arslan D.; Aslan E.; Oran B.Mucopolysaccharidosis type 6, also known as Maroteaux-Lamy syndrome, is a rare, multisystemic, progressive disease characterized by somatic involvement of varying severity and normal intelligence. N-Acetylgalactosamine-4-sulfatase enzyme is lacking and disfunction at cell, tissue, and organ levels occurs due to dermatan sulfate accumulation. Besides the findings such as coarse facial appearance, hydrocephalus, dysostosis multiplex, corneal opacity, hepatosplenomegaly, and joint stiffness, cardiac involvement is also frequently observed. Valvular heart disease, cardiomyopathy, and arrhythmia may occur in patients. In this article, we presented and discussed a mucopolysaccharidosis type 6 patient having moderate mitral valve regurgitation together with dextrocardia as a case in the light of recent literature. © Copyright 2015 by Turkiye Klinikleri.