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Surveillance of penicillin resistance of Neisseria meningitidis strains from invasive infections between 2013 and 2018 in Turkey
(TAYLOR & FRANCIS LTD, 2020) Öncel, Eda Karadağ; Ceyhan, Mehmet; Başaranoğlu, Sevgen Tanır; Gürbüz, Venhar; Aycan, Ahmet Emre; Özsürekci, Yasemin; Kurugöl, Zafer; Emiroğlu, Melike Keser; Devrim, İlker; Karbuz, Adem; Akışoğlu, Havva Özlem Altay; Gürler, Nezahat
Neisseria meningitidis (N. meningitidis) is regarded as the leading cause of bacterial meningitis in many regions of the world. The empiric antimicrobial treatment is mainly based on antimicrobial resistance and patient characteristics. We aimed to analyze susceptibility patterns of N. meningitidis strains isolated in Turkey. Invasive meningococci collected in a multicenter, hospital-based, epidemiological surveillance study of pediatric (0-18 years of age) bacterial meningitis cases between 2013 and 2018 were studied. Five isolates (8.7%) displayed resistance to penicillin-G, while 13 isolates (22.8%) had intermediate susceptibility. All isolates were cefotaxime and rifampin susceptible. The data shows appropriateness of third-generation cephalosporins in empirical use for meningococcal infections in children. Since Turkey is located in a transition zone geographically, surveillance reports are very crucial.