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Öğe Bond Strength of Five Current Adhesives to Caries-Affected Dentin(Blackwell Publishing Ltd, 2002) Şengün, Abdulkadir; Ünlü, Nimet; Özer, F.; Öztürk, B.Five current dentin adhesives were evaluated for their ability to bond to caries-affected dentin. The materials were: total etch [Solid Bond (SB)], two self-etch [Clearfil SE Bond (CSE), Etch and Prime (EP)], two one bottle [Prime and Bond 2.1 (PB), One Coat Bond (OCB)]. Sixty extracted molar teeth with proximal caries (mesial or distal) extending into mid-dentin were used. By grinding normal and caries-affected proximal surfaces, flat dentin surfaces were obtained. The surfaces were then bonded with each adhesive system and composite resins were added to the surfaces by packing the material into a cylindrical-shaped plastic matrix with an internal diameter of 2.5 mm and height of 3 mm. Shear bond testing was performed following 10 days incubation of specimens in distilled water at 37 degreesC. Results were analysed by Kruskal-Wallis ANOVA, and Mann-Whitney U multiple comparison test and Wilcoxon rank tests. The results obtained with CSE, SB, and EP were similar in caries affected and normal dentin (P > 0.05). But bonds made to normal dentin with OCB and PB were lower (P < 0.05) than bonds to caries-affected dentin. Bonding to caries-affected dentin with CSE (24.49 +/- 5.38), SB (21.49 +/- 9.15), and EP (21.19 +/- 9.17) showed shear bond strengths higher than OCB (17.43 +/- 9.78) and PB (14.10 +/- 7.94) (P < 0.05). Bonding to normal dentin with CSE (29.91 +/- 8.95) was the highest (P < 0.05). SB (21.17 +/- 5.41) and EP (17.45 +/- 6.21) showed shear bond strengths higher than OCB (11.99 +/- 10.15) and PB (10.57 +/- 4.56) (P < 0.05).Öğe Bond Strengths of Bonding Agents to Pulp Chamber Dentinal Wall(Int Amer Assoc Dental Researchi A D R/A A D R, 2002) Öztürk, B.; Özer, F.[Abstract not Available]Öğe D-dimer and D-dimer/fibrinogen ratio in predicting pulmonary embolism in patients evaluated in a hospital emergency department(MANEY PUBLISHING, 2014) Kara, Hasan; Bayır, Ayşegül; Değirmenci, Selim; Kayış, Seyit Ali; Akıncı, Murat; Ak, Ahmet; Çelik, Bülent; Doğru, Ali; Öztürk, B.Objectives: The D-dimer level, fibrinogen level, and D-dimer/fibrinogen ratio are used in the diagnosis of pulmonary embolism, but results vary. We evaluated these parameters in the diagnosis of pulmonary embolism in emergency clinic patients. Methods: In this prospective study, 200 patients (pulmonary embolism, 100 patients; no pulmonary embolism, 100 patients) had D-dimer and fibrinogen levels measured before intervention. Pulmonary embolism was diagnosed with computed tomography angiography or ventilation-perfusion scintigraphy. Results: Compared with patients who did not have pulmonary embolism, patients who had pulmonary embolism had significantly greater mean D-dimer level (pulmonary embolism, 6 +/- 7 mu g/ml; no pulmonary embolism, 1 +/- 1 mu g/ml; P <= 0.001) and D-dimer/fibrinogen ratio (pulmonary embolism, 3 +/- 3; no pulmonary embolism, 0.4 +/- 0.4; P <= 0.001), but similar mean fibrinogen levels (pulmonary embolism, 337 +/- 184 mg/dl; no pulmonary embolism, 384 +/- 200 mg/dl; not significant). In patients who had pulmonary embolism, mean D-dimer level and D-dimer/fibrinogen ratio were greater in high-risk than non-high-risk patients. With D-dimer cutoff 0.35 mu g/ml, sensitivity was high (100%) and specificity was low (27%) for pulmonary embolism. With D-dimer/fibrinogen ratio cutoff 0.13, sensitivity was high (100%) and specificity was low (37%) for pulmonary embolism. Conclusion: A D-dimer level <0.35 mu g/ml may exclude the diagnosis of pulmonary embolism. At a D-dimer cutoff 0.5 mu g/ml and D-dimer/fibrinogen ratio cutoff 1.0, the D-dimer/fibrinogen ratio may have better specificity than D-dimer level in the diagnosis of pulmonary embolism, but the D-dimer/fibrinogen ratio may lack sufficient specificity in screening.Öğe The effect of allergic rhinitis treatment on serum ischemia modified albumin levels in children with allergic rhinitis(WILEY-BLACKWELL, 2013) Vatansev, Hüsamettin; Akyürek, Fikret; Artaç, Hasibe; Atıcı, Seval; Öztürk, B.; Sivrikaya, Abdullah[Abstract not Available]Öğe Effect of Altered Eating Habits and Periods During Ramadan Fasting on Intraocular Pressure, Tear Secretion, Corneal and Anterior Chamber Parameters(NATURE PUBLISHING GROUP, 2010) Kerimoglu, H.; Öztürk, B.; Gündüz, K.; Bozkurt, B.; Kamış, U.; Okka, M.Purpose To determine whether altered eating habits and periods, especially the pre-dawn meal, during Ramadan fasting have any significant effect on intraocular pressure (IOP), tear secretion, corneal and anterior chamber parameters. Methods IOP, basal tear secretion (BTS), reflex tear secretion (RTS), and Pentacam measurements of 31 healthy volunteers were performed at 0800 and 1600 hours during Ramadan fasting and 1 month later during non-fasting period. Results Comparison of measurements between fasting and non-fasting periods at 0800 hours revealed significantly higher values for IOP (P = 0.005), RTS (P = 0.006), and BTS (P = 0.014) during fasting. Conversely at 1600 hours, IOP = was significantly lower during fasting (P = 0.013) and no statistically significant difference was noted for RTS and BTS. IOP showed a diurnal variation of 2.45 mmHg (P < 0.001) and BTS showed a 3.06 mm decrease (P = 0.04) during the fasting period. No significant differences could be found in the corneal and anterior chamber parameters during fasting and non-fasting periods. Conclusions Our results revealed that fluid loading at the pre-dawn meal during Ramadan fasting might increase the IOP = and tear secretion in the early morning period and these values decrease remarkably at the end of 12 h of fasting due to dehydration.Öğe Effect of Duration of Macular Detachment on Early Visual Acuity Results in Macula of Rhegmatogenous Retinal Detachments(2009) Kerimoğlu, H.; Adam, M.; Turan, M.; Öztürk, B.; Pekel, H.; Okudan, S.Purpose: To evaluate the effect of the duration of macular detachment on best corrected visual acuity in eyes with rhegmatogenous retinal detachment treated with pneumatic retinopexy. Materials and Methods: The charts of patients with rhegmatogenous retinal detachment who had macular detachment within 2 weeks period and treated succesfully with pneumatic retinopexy between May 2006 and May 2009 in our clinic were reviewed retrospectively. 47 eyes were grouped according to their duration of macular detachment as eyes treated within 1-5 days (21 eyes), 6-10 days (14 eyes) and 11-14 days (12 eyes) and also grouped as eyes treated within first week (26 eyes) and second week (21 eyes) and the best corrected visual acuity 3 months after the operation was compared among the groups. Results: There was a significant difference between visual acuities of the 3 groups divided as 1-5, 6-10 and 11-14 days according to duration of macular detachment (p<0.001, Kruskal Wallis test). The difference between visual acuities of eyes treated within first week (0.56±0.19) and second week (0.32±0.13) was also significant (p<0.001, Mann-Whitney test). Conclusion: Postoperative visual acuity decreases while the duration of macular detachment increases in eyes treated with pneumatic retinopexy assessed in 3 and 2 time periods. Duration of macular detachment is an important prognostic factor for the prediction of postoperative visual acuity.Öğe The Effect of Simulated Intrapulpal Pressure on Bond Strength to Enamel and Dentine(WILEY, 2003) Şengün, A.; Öztürk, B.; Özer, F.The purpose of this study was to evaluate the effect of simulated intrapulpal pressure on the shear bond strength (SBS) of a self-etching bonding system (Clearfil Liner Bond II) to both enamel and dentine surfaces. Forty-two caries-free human molar teeth were randomly assigned to two equal groups (n =21). One group of 21 teeth was connected to a special pulpal pressure machine, which is developed to simulate in vivo conditions. The buccal and lingual surfaces of the teeth were prepared with a diamond wheel to create flat dentine and enamel surfaces. A self-etching bonding system was then applied under pulpal pressure and 2.5 mm diameter composite cylinders were bonded to the prepared surfaces. The samples were then stored in distilled water at room temperature for 24 h under pulpal pressure before SBS was tested. The second restored group was used as a control and the teeth were not connected to the pulpal pressure apparatus during material application and test procedures. They were stored for 24 h in distilled water at room temperature before the SBS test. Fracture analysis of the enamel and dentinal surfaces was performed using a stereomicroscope. Shear bond strength values to dentine was significantly reduced with pulpal pressure (P < 0.001). However, in the enamel, SBS was increased (P < 0.001). In the control group, the SBS values to dentine and enamel did not show any significant difference (P > 0.05). Based on these results, it can be concluded that further analysis of enamel histology and bonding mechanisms are needed.Öğe The effect of vitamin D on MCF-7 breast cancer cell metabolism(COMENIUS UNIV, 2017) Saraçlıgil, B.; Öztürk, B.; Ünlü, Ali; Abuşoğlu, Sedat; Tekin, G.The role of vitamin D in calcium absorption and bone health is known. The studies revealed that vitamin D modulates breast cancer cell growth and it is also associated with a reduced breast cancer risk. The primary objective of this study was to highlight the metabolic effect of Vitamin D on MCF-7 breast cancer cell line. For that purpose, we checked the apoptosis, energy, amino-acid and acylcarnitine levels in cancer cells, that the study propose, that la, 25(OH)(2)D-3 could inhibit cell growth in a dose and time dependent manner. IC50 dose was calculated as 145 nM for vitamin D. We observed the apoptosis level in vitamin D groups, which were 18, 28 and 38.5 % at 24, 48 and 72 hours, respectively. During metabolic screening analysis, it was observed that glutamine, methionine and glutamic acid levels were treated more by Vitamin D groups in cell line and also, that acylcarnitine level was increased in 24 and 48 hour groups when compared to the control, but decreased in 72 hours. Further studies are needed to analyze the role of amino acids and acylcarnitines for early apoptosis and cancer metabolism (Tab. 2, Fig. 4, Ref. 24). Text in PDF www.elis.sk.Öğe Levels of arginine and its products in dialysis patients(VERDUCI PUBLISHER, 2014) Uğurcu, Veli; Vatansev, Hüsamettin; Ünlü, Ali; Sivrikaya, Abdullah; Akyürek, Fikret; Öztürk, B.; Kıyıcı, AyselOBJECTIVES: Chronic renal failure is among significant public health problems all over the world. Despite advances in diagnosis and treatment approaches, cardiovascular morbidity and mortality is still high in chronic renal failure patients on dialysis. The aim this study is to investigate the importance of arginine, asymmetric dimethylarginine (ADMA) and nitric oxide (NO) levels in the pathophysiology of cardiovascular morbidity and mortality in patients with dialysis treatment program. PATIENTS AND METHODS: 53 patients with chronic renal failure receiving hemodialysis treatment and 34 healthy persons were participated to the study. Arginine and ADMA levels were measured by high-performance liquid chromatography (HPLC) fluorescence detector. NO levels were assessed by a colorimetric method. Albumin, urea, creatinine levels was performed using the spectrophotometric method. RESULTS: Arginine levels were similar in dialysis patients when compared to the control group. Similarly NO levels did not show any difference between patient group and the control group. ADMA levels were found to be significantly high in dialysis patients compared to the control group (p < 0.005). Arginine/ADMA ratio was lower in the patient group compared to the control group (p < 0.001). Dialysis patients who have diagnosed coronary artery disease had low levels of albumin and creatinine. Arginine levels, ADMA levels and NO levels did not show any difference in the patients with coronary artery disease or not (p > 0.05). Arginine levels were significantly higher in men compared to women. Pearson correlation analysis showed that there was a correlation between NO and arginine levels. Arginine and Arginine/ADMA showed a positive correlation while ADMA and arginine/ADMA levels showed a negative correlation. CONCLUSIONS: As a result, our data showed that ADMA clearance was impaired in hemodialysis patients. Increase in ADMA levels may play a role in atherosclerosis dependent morbidity and mortality.Öğe The levels of total oxidant status, total antioxidant status and homocystein in hyperhydrosis patients(WILEY-BLACKWELL, 2013) Vatansev, H.; Öncel, M.; Öztürk, B.; Gün, F.; Baran, H.; Sunam, G. S.; Abuşoğlu, Sedat[Abstract not Available]Öğe Protective effects of grape seed proanthocyanidin extract in experimental obstructive jaundice(WILEY-BLACKWELL, 2013) Vatansev, Hüsamettin; Savda, M.; Akyürek, Fikret; Çakır, Murat; Öztürk, B.; Ünlü, Ali[Abstract not Available]Öğe Specimen processing and handling for plasma ammonia measurement(WILEY-BLACKWELL, 2016) Saraçlıgil, B.; Abuşoğlu, Sedat; Akyürek, F.; Öztürk, B.[Abstract not Available]
