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  • Küçük Resim Yok
    Öğe
    Combined occipital, transtentorial, supracerebellar, transsinus approach for pineal region teratoma
    (Turkish Neurosurgical Society, 2006) Cengiz Ş.L.; Üstün M.E.; Avunduk M.
    An 11-year-old boy with a large pineal region mass was admitted to our clinic. The preliminary diagnosis was teratoma. Tumor resection was carried out via combined occipital, transtentorial, supracerebellar, transsinus approach. The tumor tissue was completely resected, and no operative complication other than transient Parinaud syndrome was noted. The histological diagnosis was teratoma, grade 2. After three courses of chemotherapy, the patient underwent external irradiation. He remained asymptomatic with no signs of recurrence 15 months after the surgery. The combination of occipital, transtentorial, supracerebellar, transsinus approach provides excellent views and workspace above and below the tentorial notch. Transverse sinus section is not mandatory for this approach, but sectioning of the unilateral transverse sinus and the tentorium along the rectal sinus allows retraction of the falx and the underlying brain to the opposite side. Thus, a much wider horizontal and vertical projection is obtained. This approach enables more extensive tumor removal for large pineal region tumors.
  • Küçük Resim Yok
    Öğe
    A comparison of the effects of Adcon-L Mitomycin C and sodium hyaluronate in experimental epidural fibrosis in rabbits [Tavşanlarda Oluşturulan Deneysel Epidural Fibroziste Adcon-L, Mitomisin-C ve Sodyum Hyaluronat'ın Etkilerinin Karşılaştırılması]
    (Ege University Press, 2011) Kaya B.; Esen H.H.; Üstün M.E.
    Objective: Epidural fibrosis and leptomeningeal adhesion formation are among the common causes of failed back surgery syndrome. Various materials have been used to prevent the compressive effect of postoperative epidural fibrosis on neural structures. The effects of Adcon L, Mitomycin C and sodium hyaluronate on epidural fibrosis compared in this experimental study. Methods: 28 rabbits divided into 4 different groups. L5 total laminectomy performed under ketamine and xyzlazine anasthesia. Group1 settled as control group and had no medications after laminectomy. Adcon L in group 2, Mitomycin C in group3 and sodium hyaluronate in group 4 were applied to laminectomy area. All groups sacrified 6 weeks after laminectomy. Histologic slices were invastigated under light microscobe according to their histopathological features and the groups were compared. Result: Grade 3 fibrosis determinated in group1. Statistically significant differences between group1 and all other groups were obtained (p<0.05) No statistically significant differences was determinated between group 2, 3 and 4 respectively. Conclusions: All medications we use decreased postoperative epidural fibrosis in this study. But further studies are needed for routine application of these medications.