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Öğe CAPRINE ARTHRITIS ENCEPHALITIS VIRUS INFECTION IN KIDS WITH ARTHRITIS(INDIAN VETERINARY JOURNAL, 2008) Acar, A.; Yavru, S.; Kale, M.; Bulut, O.; Avci, O.; Pehlivanoglu, F.Infection by caprine arthritis encephalitis virus (CAEV) is a worldwide cause of slowly progressing inflammatory disease of joints, mammary gland, lung and less commonly brain of mature goats. Chronic, proliferative arthritis in mature goats is the predominant clinical disease manifestation of CAE (Cheevers et al, 1988). The present study records a clinical presentation of CAE, in kids I to 3 months of age, with arthritis.Öğe A case with distal trisomy 10q24(SPRINGER, 2005) Tasdemir, P.; Zamani, A. G.; Demirel, S. S.; Acar, A.[Abstract not Available]Öğe A case with mental retardation and a translocation between chromosomes 6 and Y(KARGER, 1997) Durakbaşı, Hatice Gül Dursun; Zamani, A.; Acar, H.; Acar, A.[Abstract not Available]Öğe Change in some quality parameters and oxidative stability of olive oils with regard to ultrasound pretreatment, depitting and water addition(Elsevier B.V., 2020) Rigane, G.; Yahyaoui, A.; Acar, A.; Mnif, S.; Salem, R. B.; Arslan, D.Ultrasound pretreatment with different times (0, 4, 8, 10 min) on olive paste previous malaxation of olive oil extraction along with depitting and water application procedures were studied. The effects of these procedures on oil yield, quality parameters and oxidative stability have been studied. Therefore, the olive oil yield increase with increasing time of ultrasound treatment. On the other hand, the application of ultrasound did not adversely affect the quality characteristics, as well as the antioxidant activity, when comparing with untreated paste. Furthermore, the oxidative stability data, we can conclude that ultrasound treatment can affect the olive oil oxidative stability. This study could provide useful information for industry to produce olive oil with high yield and quality. © 2020Öğe Chromosomal Abnormalities in Mentally Retarded Children in the Konya Region - Turkey(Medecine Et Hygiene, 2000) Cora, T.; Demirel, S.; Acar, A.Etiology of mental retardation is diverse. 120 Students from 11 special training, education, and rehabilitation subclasses were investigated cytogenetically For determining the contribution of chromosomal abnormalities to mild mental retardation. 23 of the 120 children (19%) had chromosomal abnormalities: thirteen cases a classical trisomy 21 (the male: Female ratio was 9:4), three a balanced autosomal reciprocal translocation, one a pericentric inversion of chromosome 9, and six fragile-X syndrome (The male: female ratio was 5:1).Öğe Corticosteroid Treatment for Prevention of Prematurity Complications(2002) Çelik, Çetin; Acar, A.; Çiçek, N.; Koç, H.; Ak, D.; Akyürek, CemalettinObjective: To investigate of efficiency to corticosteroid treatment for prevention of respiratory distress syndrome and other prematurity complications. Materials and Methods: One thousand and six babies born at 26-36th gestational age were investigated for following parameters; the development of respiratory distress syndrome, necessity of surfactant therapy, mean duration of daily ventillatory support, rates of Grade III or IV intraventricular hemorrhage, and periventricular leukomalacia, necrotizing enterocolitis, proven neonatal sepsis and neonatal death. Antenatal steroids were administered in the form of two 12-mg intramuscular doses of betamethasone 12 h apart as a total 24 mg in the 24 h and repeat courses of two 12 mg of betamethasone every 7 days after the first dose of the last course if undelivered. Babies were divided into 4 groups based on betamethasone treatment: The first group or control group didn't received treatment; the second group received treatment and delivered within 12 h after first injection; the third group delivered 12-24 h after first injection; and fourth group delivered at least 24 h after first injection. The patients ongoing pregnancy at least 1 week were divided into two groups as a single dose and multiple courses in once a week. Results: Significant difference for development of respiratory distress syndrome between fourth group and others was found (p=0.029). There were significant difference for respiratory distress syndrome rate in hypertansive and premature rupture of membranes groups between fourth group and control group (p=0.002, p=0.041). There weren't significant difference for RDS between repeat doses and single dose groups (p>0.05). Conclusion: Single dose corticosteroid is an effective treatment for the development of RDS and the prevention of other prematurity complications.Öğe Detection of monosomy 22 in interphase nuclei by fluorescence in situ hybridization(KARGER, 1997) Acar, H.; Acar, Osman; Acar, A.; Üstün, Mehmet Erkan[Abstract not Available]Öğe Determination of anxiety levels of pregnant women that have nausea and vomitting(2005) Akköz, S.; Acar, A.OBJECTIVE: Determination of anxiety levels of pregnant women that have nausea and vomitting STUDY DESIGN: This study was conducted in city of Konya, Dr. Faruk Sükan Department of Obstetrics, SSK Department of Obstetrics and Selçuk University of Faculty of Medicine, Department of Obstetrics and Gynecology. Total 100 pregnant women were used as a materials. Women were divided into two groups. Groups were consisted of 50 pregnant women with the diagnoses emezis and hyperemezis and 50 healthy pregnant women (in the first and second trimester). Anxiety levels of the pregnant women were determined by (using) Beck Anxiety Envantery. Statistical analysis done with Kruskal Wallis variance analysis, Chi-Sauare and Wilcoxon sign test. RESULT(s): The questionaire that were answered by pregnant women taken into the study as a each age groups were determined, concluded that pregnant women age 17-20 were had more physiological disturbances than other age groups. Dizziness, trembling, fear of losing control and stomach problems were found to be statisticaly higher in the study group (p<0.05). Relation between age and anxiety levels were found to be statisticaly important (p<0.05). But there were not noticed relationship between week of pregnancy and anxiety levels (p>0.05). CONCLUSION: Anxiety levels in the study group were found to be statisticaly higher than in the control group (p<0.05).Öğe Determination of relation between anxiety levels and age factor of pregnant women(2007) Akköz, S.; Acar, A.OBJECTIVE: Determination of relation between anxiety levels and age factor of pregnant women STUDY DESING: This study was conducted in city of Konya, Dr. Faruk Sükan Department of Obstetrics, SSK Department of Obstetrics and Selçuk University of Faculty of Medicine, Department of Obstetrics and Gynecology. Total 100 pregnant women were used as a materials (in the first and second trimester). Anxiety levels of the pregnant women were determined by (using) Beck Anxiety Envantery. Statistical analysis done with Kruskal Wallis varian ce analysis, Chi-Square and Wilcoxon sign test. RESULTS: The questionaire that were answered by preg nant women taken into the study as a each age groups we re determined, concluded that pregnant women age 17-20 were had more physiological disturbances than other age groups. Dizziness, trembling, fear of losing control and stomach problems were found to be statisticaly higher in the study group (p<0.05). Relation between age and anxi ety levels were found to be statisticaly important (p<0.05). But there were not noticed relationship between week of pregnancy and anxiety levels (p>0.05). CONCLUSION: Anxiety levels in the old age pregnant were found to be statisticaly higher than in the young age pregnant (p<0.05).Öğe Discussion on provincial evaluation results of maternal mortality in terms of preventability: Commission decision differences in Konya(OrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2018) Durduran, Y.; Soysal, S.; Başaran, M.; Çelik, Ç.; Acar, A.; Doğan, C.; Kaya, H. M.Objective: The objective of this study was to investigate the risk factors of maternal mortality in Konya province, as well as the preventability of deaths in cases where the central and local commissions differed in their decisions. Material and Methods: Maternal mortality between 2009 and 2014 in the Konya province was screened for the cases, where the central and local Maternal Mortality Investigation Commissions gave different decisions. These differences pertain to whether the deaths were ‘preventable’ or ‘not-preventable’, differences in the first, second and third delay models, and indirect, direct and incidental deaths. The data were evaluated electronically along with a descriptive statistical analysis, differences in the decisions and compliance in the mortality rates were evaluated. Results: The median age of the deceased mothers was 28 (21–44) years and 83.3% of the mothers had at least one mortality risk factor. While the overall maternal mortality rate was 36.7% within the first 48 h after birth, the rates were highest within the first 48 h after birth (26.7%) and between the 1st and 42nd day after birth (26.7%) in indifferently assessed cases. The cause in 30% of all deaths and 33.3% of deaths with differential assessments was postpartum hemorrhage, as per the results of central Maternal Mortality Investigation Commissions. The decisions of the central and local commissions differed in terms of preventability, delay models or death classification in 50% of the deaths. Taken together, the compliance between central and local decisions was not precise in investigating maternal mortality. Conclusion: The first 48 h after birth and the postpartum period are particularly critical. The causes of death, particularly postpartum hemorrhage, should be thoroughly investigated. We recommend periodic re-evaluations of cases where different decisions were made, in order to lower the rate of preventable maternal mortality. Copyright © 2018 by Türkiye Klinikleri.Öğe Effect of pre-amniocentesis counseling on maternal pain and anxiety.(2011) Balcı, O.; Acar, A.; Mahmoud, A. S.; Çolakoğlu, M. C.The aim of this study was to evaluate the levels of anticipated and perceived pain and anxiety in expectant mothers at the times of pre-counseling, post-counseling, and post-amniocentesis and to investigate the effect of pre-amniocentesis counseling on the level of pain and anxiety. This prospective study was carried out on 240 women with singleton pregnancies at mid-trimester. The maternal pain and anxiety levels associated with the procedure were evaluated using the visual analogue scale. Perceived pain and anxiety were assessed before and after counseling the pregnant woman about amniocentesis, and after amniocentesis. Median anticipated pain levels before (pain 1) and after pre-procedure counseling (pain 2) were 5 and 4, respectively. The actual pain after the procedure (pain 3) was 3. Median levels of anxiety felt by the patients before (anxiety 1) and after pre-procedure counseling (anxiety 2) were 6 and 3, respectively, while the median anxiety after the procedure (anxiety 3) was 5. For the pain and anxiety measurements, the results for each of the comparison times were significantly different from the results for the other two comparison times (P < 0.001). Adequate pre-amniocentesis counseling effectively reduces the actual level of pain and anxiety felt by the mother undergoing mid-trimester amniocentesis. © 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology.Öğe Effects of hormone replacement therapy on psychiatric symptoms in postmenopausal women(2002) Çelik, Çetin; Özkan, I.; Albeni, Havva; Acar, A.; Akyürek, CemalettinOBJECTIVE: In this study, we aimed to determine the psychological benefits of HRT in postmenopausal women. STUDY DESIGN: 30 postmenopausal women received HRT for 3 month were entered the study in Selçuk University Faculty of Medicine Obstetrics and Gynecology Department; Menopause division. Patients were given continuos 0.625 mg/day conjugated equine estrogen and 2.5 mg/day medroxiprogesteron acetate as HRT. The patients were given Symptom Checklist 90-R (SCL 90-R), Beck Depression Scale (BDS) and Situation Anxiety Inventory I-II (STAI I-II). RESULTS: The patients received HRT for tree months were found to have significant decrease in depression according to BDS and in anxiety levels according to STAI-I and STAI-II (p=0.001, p=0.002, p=0.001). In symptom check list, all subscales and mean of general symptom were found to be decreased in thirth month of HRT. CONCLUSION: HRT has positive influence on both the somatic and psychiatric symptoms in postmenopausal period. Improvement in psychological symptoms via hormonal therapies or other interventions will probably lead to better quality of life for postmenopausal women.Öğe Effects of ovulation induction on ovarian morphology: an animal study(BLACKWELL PUBLISHING INC, 2004) Çelik, Çetin; Gezginç, Kazım; Aktan, Murad; Acar, A.; Yaman, Süleyman; Güngör, S.; Akyürek, CemalettinObjective: The aim of this study was to investigate whether the ovulation induction has relation with postneoplastic lesions. Materials and methods: Seventy-eight female, 90-day-old rats were enrolled for the trial. They were divided into three groups. In the first group, 13 rats received one cycle of ovulation induction with Follitropin Beta and human chorionic gonadotropin. The second group of 13 rats received three cycles of ovulation induction, and the third study group consisted of 13 rats which received six cycles of ovulation induction. Each group had a control group consisting of same number of rats that had not received ovulation induction. At the 12th month after the ovulation induction protocols ended, rat ovaries were extirpated for histopathological examination. In histopathological examination, malignant lesions, ovarian cyst and cyst diameter, epithelial stratification, epithelial tufting, mitotic index, polymorphism of epithelial cells and nucleus, epithelial cell nuclear diameter, chromatin density nuclear atypia, and mitotic activity in ovarian cyst epithelium were evaluated. Results: No malignant ovarian lesion was found in the three groups. Ovarian cyst development was most frequent in the rats that underwent six cycles of ovulation induction. Epithelial stratification and tufting were most frequent in the rats which underwent ovulation induction six times. Significant difference was found between induction and control groups in second and third groups for cellular and nuclear polymorphism, presence of nucleolus, and nuclear chromatin density. Conclusions: Although development of malignant lesion were not found in any of the rat ovaries after ovulation induction, increase in the prevalence of epithelial dysplasia especially with increase in the number of induction cycles shows that some ovarian pathologies can occur subsequent to ovulation induction.Öğe The effects of smoking on aneuploidy and aneuploidy frequency in infertile males: a five-colour FISH study(SPRINGER, 2005) Durakbasi-Dursun, H. G.; Zamani, A. G.; Kutlu, R.; Gorkemli, H.; Bahce, M.; Acar, A.[Abstract not Available]Öğe Epididimoorchitis as a Complication of Brucellosis(KARGER, 1995) Yurdakul, T.; Sert, U.; Acar, A.; Karalezli, G.; Akçetin, Z.A study of 84 patients who were diagnosed with epididymo-orchitis between July 1987 and September 1993 is presented, Brucellosis was a complication in 14 cases (17%), All 14 cases had elevated agglutination titers. Brucella blood culture was found to be positive in 4 of 14 cases (28.5%). Standard therapy regime (streptomycin plus tetracycline) was effective in 13 of 14 (93%) cases.Öğe Evaluation of smoking genotoxicity in Turkish young adults(2011) Zamani, A. G.; Durakbaşı, Hatice Gül Dursun; Demirel, S.; Acar, A.BACKGROUND: For the past few decades, it has been widely known in developed countries that tobacco is dangerous, but it is still insufficiently realized how big these dangers really are. AIMS: To determine and evaluate micronuclei (MN) frequencies of young smokers and nonsmokers in three different tissues (peripheric blood lymphoctes, buccal mucosa, and exfoliative urothelial cells) at the same time. MATERIALS AND METHODS: MN assay was performed on buccal mucosa, urothelial cells, and peripheric blood lymphocyte samples obtained from 15 healthy male smokers (>5 pack-years) and 15 healthy male nonsmoker controls who had not been exposed to any known genotoxic agent. STATISTICAL ANALYSIS USED: The statistical differences between smoker and nonsmoker groups were calculated by using student t test. The differences between smoker-group tissues were compared by ANOVA. RESULTS: It was found that MN frequency (mean value standard deviation) in oral mucosa cells from smokers and controls were 1.20 ± 0.22% and 0.26 ± 0.10%; in urothelial exfoliative cells, 1.29 ± 0.28% and 0.12 ± 0.08%; in peripheric blood lymphocytes, 1.53 ± 0.23% and 0.38 ± 0.12%, respectively. The mean MN frequencies in buccal mucosa, urothelial exfoliative cells, and peripheric blood lymphocytes were significantly higher in smokers than in those of controls (P<0.05). All tissues were affected from smoking, but the most destructive effect was seen in urothelial cells of smokers (P<0.05). CONCLUSIONS: Our data showed that cigarette smoke is a DNA damage causitive agent on exfoliative buccal mucosa and urothelial cells and peripheric blood lymphocytes of young smokers, but it has most destructive effect on urothelial cells.Öğe Evaluation of the results of cordocentesis(Elsevier (Singapore) Pte Ltd, 2007) Acar, A.; Balcı, O.; Gezginç, K.; Önder, C.; Çapar, M.; Zamani, A.; Acar, A.Objective: To evaluate the results of cordocentesis carried out in our clinic at Meram Medicine Faculty of Selcuk University in Konya, Turkey. Materials and Methods: Cytogenetic results and complication data were obtained by cordocentesis from 250 pregnancies performed in our clinic. Results: Adequate amount of cord blood was taken 98% of the time, the successful culture rate was 92.8%, and none of the 18 cases in which no proliferation was detected in the culture accepted a new intervention. Cordocentesis was performed in 14 cases (5.6%), because no results were obtained from amniocentesis carried out for various indications. According to cytogenetic evaluation, chromosomal abnormality was detected in 12 cases (5.17%), including four cases of trisomy 21, four cases of trisomy 18, one case of trisomy 13, one case of triploidy (69,XXX) and two cases of chromosomal inversion. Of the 250 cordocentesis cases, there were 12 (4.8%) cases of fetal loss, including four cases of rupture of membranes, four cases of abdominal pain and vaginal bleeding and four cases of a spontaneous abortus. In 53 (21.2%) cases, cordocentesis was performed because of hydrops fetalis; and of the total 12 losses, six were in this group. The fetal loss rate was 11.32% in the hydrops fetalis group. Conclusion: If cordocentesis is carried out by highly skilled physicians and optimal culture conditions are available, cordocentesis is an invasive prenatal diagnostic and therapeutic procedure that is performed secondary to amniocentesis with high accuracy and safety. In cases of hydrops fetalis in which cordocentesis is carried out, fetal loss is more likely to occur.Öğe The Frequency of Consanguinity in Konya, Turkey, and Its Medical Effects(MEDECINE ET HYGIENE, 1997) Demirel, S.; Kaplanoğlu, N.; Acar, A.; Bodur, S.; Paydak, F.This study was conducted in the town of Konya, Turkey, on 1120 randomly selected women to find out the overall rate of consanguineous marriages among couples. The frequency of consanguineous marriages was found to be 23.2 %. It was found that 14.6% of this figure was first cousin marriages and the rest was 8.6%. Consanguineous marriages were higher among women born in villages compared to those born in provinces and the town center. Based on the findings, it was not too difficult to say: the higher the level of education of women, the lower the rate of consanguineous marriages. The number of children with an abnormality was high in consanguineous marriages, while the frequency of spontaneous abortion, still-birth and infant death remained the same.Öğe How to manage intrauterine growth restriction associated with severe preeclampsia at 28-34 weeks of gestation?(2008) Gezginç, K.; Acar, A.; Peru, H.; Karataylı, R.; Çelik, Ç.; Çapar, M.Aim: To propose optimal management of intrauterine growth restriction (IUGR) cases associated with severe preeclampsia at 28-34 weeks of gestation. Methods: Two hundred pregnant women with severe preeclampsia associated with growth restricted fetuses were followed with doppler velocimetry of umbilical artery between 28-34 weeks of pregnancy. Patients were grouped according to indications for termination of pregnancy, first group consisted of severely affected doppler velocity waveforms (n:100) and the second group consisted of those whose cardiotocography and biophysic profile were unfavorable (n:100). Groups were compared according to perinatal outcomes (cesarean rates, gestational age at delivery, birth weight, Apgar scores and demand for intubation and perinatal deaths). Results: The diagnosis to delivery interval is significantly higher in the second group (p<0.05), whereas there was no significant difference between groups regarding gestational age at delivery and parity (p>0.05). Apgar scores were lower in the first group (p<0.05), and there was increased demand for intubation. Perinatal deaths were also lower in the second group (p<0.05). Cesarean rate was significantly lower compared with first group (p<0.05). Conclusion: Assessment of doppler velocimetry alone may not be enough at decision for termination of pregnancy, biophysic profile and cardiotocography should be added to confirm exact time for delivery of a premature fetus and to improve perinatal outcomes.Öğe Incidence of listeria monocytogenes infection in pregnant women with preterm labor and premature rupture of membranes(2004) Alptekin, Hüsnü; Gezginç, Kazım; Çelik, Çetin; Acar, A.; Akyürek, CemalettinOBJECTIVE: To investigate the incidence of Listeria monocytogenes infection in pregnant women with premature rupture of membranes and preterm labor. STUDY DESIGN: We chose 77 pregnant women who were between 28th to 37th weeks of gestation as the study group. Within this group, 34 patients had premature rupture of membranes and 43 had preterm labor. Forty healthy pregnant women were served as the control group to a total of 117 women to participate in the study. To detect Listeria monocytogenes infection, we used bacterial cultures and serological tests. RESULT(s): Listeria monocytogenes was diagnosed in a patient with premature labor and Listeria innocua was found in a patient with premature rupture of membranes. In total, listeriosis was detected in 2 (2.5%) patients in the study group, not statistically significant in comparison to the control group. Listeria agglutination type 4bH, 4bO, IO and IH serotypes were examined in the study group. An antibody titer of 1/160 or above was accepted as positive. In 8 patients (10.3%), positive antibody titers were detected for type 4bO and type IO, but their cultures were negative for Listeria. One out of 8 patients has premature labor, and the other 7 patients had premature rupture of membranes. An antibody titer of 1/160 or above against these four serotypes was not detected in the control group. The difference between the study and the control groups was significant in terms of antibody titers of 1/160 or above (p<0.05). CONCLUSION(s): Listeriosis is a rare preventable cause of prenatal mortality. Maternal listeriosis may causes premature birth, premature rupture of membranes and congenital infection of the newborn. In pregnant women with premature labor or premature rupture of membranes, Listeria monocytogenes should be thought as one possible etiologic factor and the infection should be treated if diagnosis is established.
