Yazar "Akhan, G." seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    EEG Findings in Etomidate Anaesthesia
    (1992) Özmen, S.; Ökeşli, S.; İlhan, N.; Akhan, G.; Otelcioğlu, S.; Ünal, F.
    This study included 30 volunteer cases (19 male, 11 female) in ASA-I group with normal electroancephalographic findings. All cases divided in 3 groups randomly and 45 minutessd prior to administration of etomidate, first group was premedicated with 0.5 mg Atropine, second group with 0.5 mg Atropine and 10 mg Diazepam and third group with 0.5 mg Atropine and 01. mg Fentanyl. Induction has been succeeded by IV 0.4 mg/kg etomidate. In order to maintain anaesthesia 0.1 mg/kg etomidate was administered intravenously at 5th minute and EEG was obtained for 15 mintures after first dosage of etomidate. The EEG findings of etomidate anaesthesia and the relation of myoclonia (the main side effect) with CNS was evaluated by EEG records. EEG findings were not affected with premedication methods and no correlation between myoclonia and EEG signs was established. However, myoclonia was decreased significantly in patients who received Fentanyl as premedication. Instead of the irregular alpha and fast activities were observed on control EEG recordings in patients anaesthetised with etomidate. The sharp waves and the suppression burst activities appeared in some cases. In conclusion attention must be paid during etomidate anaesthesia in epileptic patients or it should be avoided using etomidate in patients who has a history of epilepsy because of the possibility of provocating the seizures.
  • Küçük Resim
    Öğe
    Effect of Vitamin E Therapy on Sexual Functions of Uremic Patients in Hemodialysis
    (1992) Yeksan, M.; Polat, M.; Türk, S.; Kazancı, H.; Akhan, G.; Erdoğan, Y.; Erkul, I.
    Twenty-four uremic patients on hemodialysis who had never been treated with vitamin E or related drugs and 12 control patients with normal renal function were studied. Hemodialysis patients were randomly divided into two groups; 12 were treated with oral vitamin E (300 mg/day) for eight weeks and 12 uremic patients and 12 controls were given placebo. Serum vitamin E, prolactin, FSH, LH, and free testosterone levels were measured in all patients before and after treatment. After the vitamin E treatment serum prolactin levels were significantly decreased (50.8 vs 15.4 ng/ml, p<0.01). Vitamin E levels were significantly increased (1.11 vs 1.22 mg/dl, p<0.05). Serum FSH, LH and free testosterone were not affected. In the other two groups there were no significant changes. These results show that vitamin E treatment lowers prolactin levels in uremic hemodialysis patients. This might be due to inhibition of central prolactin secretion. Vitamin E inhibits pituitary gland hypertrophy in vitamin E-deficient rats. (Int J Artif Organs 1992; 15: 648-52)
  • Küçük Resim Yok
    Öğe
    Effect of Vitamin-E Therapy on Sexual Functions of Uremic Patients in Hemodialysis
    (WICHTIG EDITORE, 1992) Yeksan, M.; Polat, M.; Türk, S.; Kazancı, H.; Akhan, G.; Erdoğan, Y.; Erkul, I.
    Twenty-four uremic patients on hemodialysis who had never been treated with vitamin E or related drugs and 12 control patients with normal renal function were studied. Hemodialysis patients were randomly divided into two groups; 12 were treated with oral vitamin E (300 mg/day) for eight weeks and 12 uremic patients and 12 controls were given placebo. Serum vitamin E, prolactin, FSH, LH, and free testosterone levels were measured in ail patients before and after treatment. After the vitamin E treatment serum prolactin levels were significantly decreased (50.8 vs 15.4 ng/ml, p<0.01). Vitamin E levels were significantly increased (1.11 vs 1.22 mg/dl, p<0.05). Serum FSH, LH and free testosterone were not affected. In the other two groups there were no significant changes. These results show that vitamin E treatment lowers prolactin levels in uremic hemodialysis patients. This might be due to inhibition of central prolactin secretion. Vitamin E inhibits pituitary gland hypertrophy in vitamin E-deficient rats.