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    İneklerde Azaltılmış Dozda Cloprostenol Uygulamalarının Luteolitik Etkisinin Klinik Östrüs Belirtileri ve Plazma Progesteron Düzeyleri Yardımıyla İzlenmesi
    (Selçuk Üniversitesi, 1994) Tekeli, Tevfik; Aksoy, Melih; Çoyan, Kenan; Semacan, Ahmet; Özsar, Semin; Güven, Bülent; Alan, Muhammed
    In this study, the effectiveness of a reduced dose of cloprostenol injected by intravulvosubmucosal route was eva/uated for esirus induction and luteolysis in cows. The study was carried out on 43 Brown Swiss cows, age ranging 3 to 5 years old. Firstly, all cows were injected 500 mcg of c/oprostenol by intramuscular route. On the 11 th. day, cows in the first group (n: 38). Were reinjected 125 mcg of cloprostenol by intravulvo submucosal route and the remaining cows in the second group (n:5) were administered an injection of 500 rncg cloprostenol intramusculary. Blood samples to determine the p/asma progesterone /eve/s were collected on the day of second injection and tour days thereafter from 9 and 5 cows in the first and second groups, respectively. According to the obtained results; esirus rates in first and second groups were 26.3 and 1 vO %,· respective/y. On the basis of the 7 cows inseminated in the first group. pregnancy rate was 57.1 %. Progesterone /eve/s of the cows in the first group decreased alter the second injection. Although a slight decrease in progesterone /eve/s was momtored in the cows with no /uteal regression, it was never below 1 nglml. The progesterone /eve/s of the cows in the first group with luteo/ysis showed a sharp decline compared to the control group. Asa result, application of 125 mcg of cloprostenol injection into vulvar submucosa induced estrus and luteolysis in cows. lt was concluded that the higher doses of cloprostenol administrations by intravulvo-submucosal injections may provide belter results in cows.